Dr Ross Keenan
FRANZCR
Consultant Neuroradiologist
Pacific Radiology Group,
Consultant Neuroradiologist
New Zealand Brain Research Institute, Christchurch
Publications
Provided on request for non-commercial personal use by researchers.
2024
Aye, W. W., Stark, M. R., Horne, K.-L., Livingston, L., Grenfell, S., Myall, D. J., Pitcher, T.L., Almuqbel, M.M., Keenan, R. J., Meissner, W.G., Dalrymple-Alford, J., Anderson, T.J., Le Heron, C., Melzer, T. R. (2024). Early‐phase amyloid PET reproduces metabolic signatures of cognitive decline in Parkinson's disease. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 16(2),
e12601..
10.1002/dad2.12601
Reuben, A, Richmond-Rakerd, LS, Milne, B., ..., Keenan, R., ..., Melzer, T., ..., Moffitt, T.E. (2024). Dementia dementia's risk factors and premorbid brain structure are concentrated in disadvantaged areas: National register and birth-cohort geographic analyses. Alzheimer's Dementia, .
10.1002/alz.13727
2023
MacAskill, M. R., Pitcher, T. L., Melzer, T. R., Myall, D. J., Horne, K.-L., Shoorangiz, R., Almuqbel, M. M., Livingston, L., Grenfell, S., Pascoe, M. J., Marshall, E. T., Marsh, S., Perry, S. E., Meissner, W. G., Theys, C., Le Heron, C. J., Keenan, R. J., Dalrymple-Alford, J. C., Anderson, T. J. (2023). The New Zealand Parkinson’s Progression Programme. Journal of the Royal Society of New Zealand,
53, .
10.1080/03036758.2022.2111448
Whitman, E. T., Knodt, A. R., Elliott, M. L., Abraham, W. C., Cheyne, K., Hogan, S., Ireland, D., Keenan, R., Leung, J. H., Melzer, T. R., Poulton, R., Purdy, S. C., Ramrakha, S., Thorne, P. R., Caspi, A., Moffitt, T. E., Hariri, A. R. (2023). Functional topography of the neocortex predicts covariation in complex cognitive and basic motor abilities. Cerebral Cortex.
10.1093/cercor/bhad109
2022
Tippett, L. J., Cawston, E. E., Morgan, C. A., Melzer, T. R., Brickell, K. L., Ilse, C., Cheung, G., Kirk, I. J., Roberts, R. P., Govender, J., Griner, L., Le Heron, C., Buchanan, S., Port, W., Dudley, M., Anderson, T. J., Williams, J. M., Cutfield, N. J., Dalrymple-Alford, J. C., … the NZ-DPRC. (2022). Dementia Prevention Research Clinic: A longitudinal study investigating factors influencing the development of Alzheimer’s disease in Aotearoa. Journal of the Royal Society of New Zealand.
10.1080/03036758.2022.2098780
2021
Basukala, D., Mukundan, R., Lim, A., Hurrell, M. A., Keenan, R. J., Dalrymple-Alford, J. C., Anderson, T. J., Myall, D. J., Melzer, T. R. (2021). Automated segmentation of substantia nigra and red nucleus using quantitative susceptibility mapping images: application to Parkinson’s disease. Computers & Electrical Engineering,
91, .
10.1016/j.compeleceng.2021.107091
Elliott, M. L., Caspi, A., Houts, R. M., Ambler, A., Broadbent, J. M., Hancox, R. J., Harrington, H., Hogan, S., Keenan, R., Knodt, A., Leung, J. H., Melzer, T. R., Purdy, S. C., Ramrakha, S., Richmond-Rakerd, L. S., Righarts, A., Sugden, K., Thomson, W. M., Thorne, P. R., Williams, B. S., Wilson, G., Hariri, A. R., Poulton, R., Moffitt, T. E. (2021). Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy. Nature Aging,
1, .
10.1038/s43587-021-00044-4
Richmond-Rakerd, L. S., Caspi, A., Ambler, A., d’Arbeloff, T., de Bruine, M., Elliott, M., Harrington, H., Hogan, S., Houts, R. M., Ireland, D., Keenan, R., Knodt, A. R., Melzer, T. R., Park, S., Poulton, R., Ramrakha, S., Rasmussen, L. J. H., Sack, E., Schmidt, A. T., … Moffitt, T. E. (2021). Childhood self-control forecasts the pace of midlife aging and preparedness for old age. Proceedings of the National Academy of Sciences,
118, .
10.1073/pnas.2010211118
Romer, A. L., Elliott, M. L., Knodt, A. R., Sison, M. L., Ireland, D., Houts, R., Ramrakha, S., Poulton, R., Keenan, R., Melzer, T. R., Moffitt, T. E., Caspi, A., Hariri, A. R. (2021). Pervasively thinner neocortex as a transdiagnostic feature of general psychopathology. American Journal of Psychiatry,
178.
10.1176/appi.ajp.2020.19090934
2020
Almuqbel, M., Melzer, T. R., Oram, B. J., Keenan, R. J. (2020). Compressed sensing in metal hip imaging: our experience. MAGNETOM Flash,
77, .
Borlase, N., Myall, D., Melzer, T., Livingston, L., Watts, R., Keenan, R., MacAskill, M., Anderson, T., Dalrymple-Alford, J. (2020). Microstructural integrity of the major nuclei of the thalamus in Parkinson’s disease. bioRxiv, .
10.1101/2020.05.21.109660
Melzer, T.R., Keenan, R.J., Leeper, G.J., Kingston-Smith, S., Felton, S.A., Green, S.K., Henderson, K.J., Palmer, N.J., Shoorangiz, R., Almuqbel, M.M., Myall, D.J. (2020). Test-retest reliability and sample size estimates after MRI scanner relocation. Neuroimage 211, .
10.1016/j.neuroimage.2020.116608
Romer, A.L., Elliott, M.L., Knodt, A.R., Sison, M.L., Ireland, D., Houts, R., Ramrakha, S., Poulton, R., Keenan, R., Melzer, T.R., Moffitt, T.E., Caspi, A., Hariri, A.R. (2020). Pervasively thinner neocortex as a transdiagnostic feature of general psychopathology. American Journal of Psychiatry.
10.1176/appi.ajp.2020.19090934
Senadeera, S. C., Palmer, D. G., Keenan, R., Beharry, J., Yuh Lim, J., Hurrell, M. A., Mouthaan, P., Fink, J., Wilson, D., Lim, A., Wu, T. Y. (2020). Left atrial appendage thrombus detected during hyperacute stroke imaging is associated with atrial fibrillation. Stroke,
51, .
10.1161/STROKEAHA.120.030258
d’Arbeloff, T., Elliott, M. L., Knodt, A. R., Melzer, T. R., Keenan, R., Ireland, D., Ramrakha, S., Poulton, R., Anderson, T.J., Caspi, A., Moffitt, T. E., Hariri, A. R. (2020). White matter hyperintensities are common in midlife and already associated with cognitive decline. Brain Communications,
1(1), .
10.1093/braincomms/fcz041
2019
Elliott, M. L., Knodt, A. R., Cooke, M., Kim, M. J., Melzer, T. R., Keenan, R., … Hariri, A. R. (2019). General functional connectivity: Shared features of resting-state and task fMRI drive reliable and heritable individual differences in functional brain networks. NeuroImage,
189, .
0.1016/j.neuroimage.2019.01.068
Melzer, T. R., Stark, M. R., Keenan, R. J., Myall, D. J., MacAskill, M. R., Pitcher, T. L., Livingston, L., Grenfell, S., Horne, K., Young, B., Pascoe, M., Almuqbel, M. A., Wang, J., Marsh, S., Miller, D. H., Dalrymple-Alford, J. C., Anderson, T. J. (2019). Beta amyloid deposition is not associated with cognitive impairment in Parkinson’s disease. Frontiers in Neurology,
10, .
10.3389/fneur.2019.00391
Romer, A.L., Knodt, A.R., Sison, M.L., Ireland, D., Houts, R., Ramrakha, S., Poulton, R., Keenan, R., Melzer, T.R., Moffitt, T.E. and Caspi, A. (2019). Replicability of structural brain alterations associated with general psychopathology: evidence from a population-representative birth cohort. Molecular Psychiatry, .
10.1038/s41380-019-0621-z
2018
Almuqbel, M. M., Leeper, G., Palmer, D. N., Mitchell, N. L., Russell, K. N., Keenan, R., Melzer, T. R. (2018). Practical implications of motion correction with motion insensitive radial k-space acquisitions in MRI. British Journal of Radiology,
91:20170593, .
10.1259/bjr.20170593
2016
Almuqbel, M., Melzer, T.R., Myall, D.J., MacAskill, M.R., Pitcher, T.L., Livingston, L., Wood, K., Keenan, R.J., Dalrymple-Alford, J.C., Anderson, T.J. (2016). Metabolite ratios in the posterior cingulate cortex do not track cognitive decline in Parkinson's disease in a clinical setting. Parkinsonism & Related Disorders,
22, .
10.1016/j.parkreldis.2015.11.008
2015
Darlow, B. A., Horwood, L. J., Woodward, L. J., Elliott, J. M., Troughton, R. W., Elder, M. J., Epton, M. J., Stanton, J. D., Swanney, M. P., Keenan, R., Melzer, T. R., McKelvey, V. A., Levin, K., Meeks, M. G., Espiner, E. A., Cameron, V. A., Martin, J. (2015). The New Zealand 1986 very low birth weight cohort as young adults: mapping the road ahead. BMC Pediatrics,
15, .
10.1186/s12887-015-0413-9
Melzer, T.R., Myall, D.J., MacAskill, M.R., Pitcher, T.L., Livingston, L., Watts, R., Keenan, R.J., Dalrymple-Alford, J.C., Anderson, T.J. (2015). Tracking Parkinson's disease over one year with multimodal magnetic resonance imaging in a group of older patients with moderate disease. PLOS ONE,
10, .
10.1371/journal.pone.0143923
2014
Le Heron, C. J., Wright, S. L., Melzer, T. R., Myall, D. J., MacAskill, M. R., Livingston, L., Keenan, R. J., Watts, R., Dalrymple-Alford, J. C. , Anderson, T.J. (2014). Comparing cerebral perfusion in Alzheimer's disease and Parkinson's disease dementia: an ASL-MRI study. Journal of Cerebral Blood Flow & Metabolism,
34, .
10.1038/jcbfm.2014.40
2013
Melzer, T. R., Watts, R., MacAskill, M. R., Pitcher, T. L., Livingston, L., Keenan, R., Dalrymple-Alford, J. C., Anderson, T. J. (2013). White matter microstructure deteriorates across cognitive stages in Parkinson disease. Neurology,
80, .
10.1212/WNL.0b013e3182929f62
2012
Melzer, T. R., Watts, R., MacAskill, M. R., Pitcher, T. L., Livingston, L., Keenan, R., Dalrymple-Alford, J. C., Anderson, T. J. (2012). Grey matter atrophy in cognitively impaired Parkinson’s disease. Journal of Neurology, Neurosurgery & Psychiatry,
83(2), .
10.1186/2047-9158-1-17
Pitcher, T. L., Melzer, T. R., MacAskill, M. R., Graham, C. F., Livingston, L., Keenan, R. J., Watts, R., Dalrymple-Alford, J. C., Anderson, T. J. (2012). Reduced striatal volumes in Parkinson’s disease: a magnetic resonance imaging study. Translational Neurodegeneration,
1(1), .
10.1186/2047-9158-1-17
2011
Melzer, T. R., Watts, R., MacAskill, M. R., Pearson, J. F., Rüeger, S., Pitcher, T. L., Livingston, L., Graham, C., Keenan, R., Shankaranarayanan, A., Alsop, D. C., Dalrymple-Alford, J. C., Anderson, T. J. (2011). Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson’s disease. Brain,
134(3), .
10.1093/brain/awq377
2010
Dalrymple-Alford, J. C., MacAskill, M. R., Nakas, C. T., Livingston, L., Graham, C., Crucian, G. P., Melzer, T. R., Kirwan, J., Keenan, R., Wells, S., Porter, R. J., Watts, R., Anderson, T.J. (2010). The MoCA: Well-suited screen for cognitive impairment in Parkinson’s disease. Neurology,
75, .
10.1212/WNL.0b013e3181fc29c9
Abstracts and Short papers
2020
d'Arbeloff, T., Cooke, M., Knodt, A., Sison, M., Ramrakha, S., Keenan, R., Poulton, R., Hariri, A. R., Caspi, A., Moffitt, T. E. (2020). Better cardiovascular fitness is associated with better structural brain integrity in midlife: A population‐representative birth cohort study. Alzheimer's & Dementia, .
10.1002/alz.037983
2019
d'Arbeloff, T., Elliott, M., Knodt, A., Melzer, T., Keenan, R., Ireland, D., … & Hariri, A. (2019). White matter lesions are common in midlife and associated with cognitive decline. Biological Psychiatry, 85(10),
S213.
10.1016/j.biopsych.2019.03.539
2018
Basukala, D., Mukundan, R., Melzer, T., Keenan, R. (2018). Segmentation of substantia nigra using weighted thresholding method, In 2018 International Conference on Image and Vision Computing New Zealand (IVCNZ) (pp. 1-6).
Basukala, D., Mukundan, R., Melzer, T., Keenan, R. (2018). Segmentation of substantia nigra for the automated characterization of Parkinson’s disease. In 2018 IEEE International Conference on Image Processing,
Applications an.
2016
Melzer, TR, Keenan, RJ, Myall, DJ, Kaur, G, Livingston, L, Horne, K, Marsh, S, MacAskill, MR, Dalrymple-Alford, JC, Anderson, TJ (2016). Amyloid imaging and cognition in Parkinson’s disease: Interim report. Proceedings of the 34th International Winter Conference on Brain Research, .
2015
Melzer, TR, Myall, DJ, MacAskill, MR, Livingston, L, Pitcher, TL, Watts, R, Keenan, RJ, Dalrymple-Alford, JC, Anderson, TJ (2015). White matter lesions contribute to future dementia in Parkinson’s disease. Proceedings of the 21st Annual Meeting of the Organization for Human Brain Mapping.
2014
Melzer, T., Myall, D., Livingston L., , Wood, K., Pitcher, T., Keenan, R., MacAskill, M., Dalrymple-Alford, J. , Anderson, T. (2014). White matter lesions - a factor in developing dementia in patients with Parkinsons disease. Proceedings of the International Australasian Winter Conference on Brain Research (AWCBR), Queenstown, New Zealand,
32, .
2013
Dalrymple-Alford, J. C., Livingston, L., Melzer, T. R., Wood, K., Goh, T. J., Pitcher, T. L., Graham, C. F., Keenan, R. J., MacAskill, M. R. , Anderson, T.J. (2013). Current perspectives on Parkinsons disease: Cognition to the fore. Proceedings of the 31st Australasian Winter Conference on Brain Research 2013, Queenstown, Volume 31,
Abstract 29.
Dalrymple-Alford, J., McCurrie, C., Anderson, T., Watts, R., MacAskill, M., Pitcher, T., Livingston, L., Keenan, R. , Melzer, T. (2013). Domain specific cognitive dysfunction in Parkinson’s Disease and associated pattern of grey matter atrophy. Proceedings of the Movement Disorders Society 17th International Congress - Sydney,
Abstract 572..
Grenfell, S., Melzer, T. R., Young, B., Wang, A, Livingston, L., Keenan, R. J., MacAskill, M. R., Anderson, T. J. , Dalrymple-Alford, J.C. (2013). Reduced default mode network connectivity and autobiographical memory in mild cognitive impairment. Proceedings of the 31st Australasian Winter Conference on Brain Research 2013, Queenstown,
Volume 31, .
Melzer, T. R., Watts, R., MacAskill, M., Pitcher, T., Livingston, L., Keenan, R., Dalrymple-Alford, J. , Anderson, T. (2013). Serial DTI and cognitive decline in Parkinsons disease. Proceedings of the Movement Disorders Society 17th International Congress, Sydney, Movement Disorders,
28 Supplement 1, .
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