Leslie Livingston

BA (Hons)

Assistant Research Fellow

New Zealand Brain Research Institute, Christchurch

Phone: (+64 3) 928 1330

Publications

Provided on request for non-commercial personal use by researchers.

2024

Download Early‐phase amyloid PET reproduces metabolic signatures of cognitive decline in Parkinson's disease.
Aye, W. W., Stark, M. R., Horne, K.-L., Livingston, L., Grenfell, S., Myall, D. J., Pitcher, T.L., Almuqbel, M.M., Keenan, R. J., Meissner, W.G., Dalrymple-Alford, J., Anderson, T.J., Le Heron, C., Melzer, T. R. (2024). Early‐phase amyloid PET reproduces metabolic signatures of cognitive decline in Parkinson's disease. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 16(2), e12601.. 10.1002/dad2.12601
Download Higher Frequency of Stuttered Disfluencies Negatively Affects Communicative Participation in Parkinson's Disease.
Gooch, E., Melzer, T.R., Horne, K.L., Grenfell, S., Livingston, L., Pitcher, T., Dalrymple-Alford, J.C., Anderson, T.J., McAuliffe, M.J., Theys, C. (2024). Higher Frequency of Stuttered Disfluencies Negatively Affects Communicative Participation in Parkinson's Disease. Journal of Speech Language and Hearing Research, 1-12. 10.1044/2024_JSLHR-24-00018
Download Cross-Sectional and Longitudinal Association of Clinical and Neurocognitive Factors With Apathy in Patients With Parkinson Disease.
Le Heron, C., Horne, K. L., MacAskill, M. R., Livingston, L., Melzer, T. R., Myall, D., Pitcher, T., Dalrymple-Alford, J., Anderson, T., Harrison, S. (2024). Cross-Sectional and Longitudinal Association of Clinical and Neurocognitive Factors With Apathy in Patients With Parkinson Disease. Neurology, 102(12), e209301. 10.1212/WNL.0000000000209301

2023

Download The New Zealand Parkinson’s Progression Programme.
MacAskill, M. R., Pitcher, T. L., Melzer, T. R., Myall, D. J., Horne, K.-L., Shoorangiz, R., Almuqbel, M. M., Livingston, L., Grenfell, S., Pascoe, M. J., Marshall, E. T., Marsh, S., Perry, S. E., Meissner, W. G., Theys, C., Le Heron, C. J., Keenan, R. J., Dalrymple-Alford, J. C., Anderson, T. J. (2023). The New Zealand Parkinson’s Progression Programme. Journal of the Royal Society of New Zealand, 53, 466-488. 10.1080/03036758.2022.2111448

2021

Download Higher perceived stress and exacerbated motor symptoms in Parkinson's disease during the COVID-19 lockdown in New Zealand.
Blakemore, R. L., Pascoe, M. J., Horne, K. L., Livingston, L., Young, B. N., Elias, B., Goulden, M., Grenfell, S., Myall, D. J., Pitcher, T. L., Dalrymple-Alford, J. C., Le Heron, C. J., Anderson, T. J., MacAskill, M. R. (2021). Higher perceived stress and exacerbated motor symptoms in Parkinson's disease during the COVID-19 lockdown in New Zealand. The New Zealand Medical Journal, 134, 44-51.
Download Neuropsychiatric symptoms are associated with dementia in Parkinson’s disease but not predictive of it.
Horne, K., MacAskill, M. R., Myall, D. J., Livingston, L., Grenfell, S., Pascoe, M. J., Young, B., Shoorangiz, R., Melzer, T. R., Pitcher, T. L., Anderson, T. J., Dalrymple‐Alford, J. C. (2021). Neuropsychiatric symptoms are associated with dementia in Parkinson’s disease but not predictive of it. Movement Disorders Clinical Practice, 8, 390-399. 10.1002/mdc3.13151

2020

Download Microstructural integrity of the major nuclei of the thalamus in Parkinson’s disease.
Borlase, N., Myall, D., Melzer, T., Livingston, L., Watts, R., Keenan, R., MacAskill, M., Anderson, T., Dalrymple-Alford, J. (2020). Microstructural integrity of the major nuclei of the thalamus in Parkinson’s disease. bioRxiv, 2020.05.21.1096. 10.1101/2020.05.21.109660
Download Cognitive tests that identify high risk of conversion to dementia in Parkinson's disease.
Myall, D.J., Horne, K., MacAskill, M.R., Livingston, L., Pitcher, T.L., Melzer, T.R., Geurtsen, G.J., Anderson, T.J., Dalrymple-Alford, J.C. (2020). Cognitive tests that identify high risk of conversion to dementia in Parkinson's disease. bioRxiv, 2020.05.31.1268. 10.1101/2020.05.31.126870

2019

Download Beta amyloid deposition is not associated with cognitive impairment in Parkinson’s disease.
Melzer, T. R., Stark, M. R., Keenan, R. J., Myall, D. J., MacAskill, M. R., Pitcher, T. L., Livingston, L., Grenfell, S., Horne, K., Young, B., Pascoe, M., Almuqbel, M. A., Wang, J., Marsh, S., Miller, D. H., Dalrymple-Alford, J. C., Anderson, T. J. (2019). Beta amyloid deposition is not associated with cognitive impairment in Parkinson’s disease. Frontiers in Neurology, 10, 391. 10.3389/fneur.2019.00391

2017

Download Caregiver burden is increased in Parkinson’s disease with mild cognitive impairment (PD-MCI).
Jones, A. J., Kuijer, R. G., Livingston, L., Myall, D., Horne, K., MacAskill, M., Pitcher, T., Barrett, P. T., Anderson, T. J., Dalrymple-Alford, J. C. (2017). Caregiver burden is increased in Parkinson’s disease with mild cognitive impairment (PD-MCI). Translational Neurodegeneration, 6(17). 10.1186/s40035-017-0085-5

2016

Download Metabolite ratios in the posterior cingulate cortex do not track cognitive decline in Parkinson's disease in a clinical setting.
Almuqbel, M., Melzer, T.R., Myall, D.J., MacAskill, M.R., Pitcher, T.L., Livingston, L., Wood, K., Keenan, R.J., Dalrymple-Alford, J.C., Anderson, T.J. (2016). Metabolite ratios in the posterior cingulate cortex do not track cognitive decline in Parkinson's disease in a clinical setting. Parkinsonism & Related Disorders, 22, 54-61. 10.1016/j.parkreldis.2015.11.008
Download Different PD-MCI criteria and risk of dementia in Parkinson’s disease: Four year longitudinal study.
Wood, K., Myall, D.J., Livingston, L., Melzer, T.R., Pitcher, T.L., MacAskill, M.R., Geurtsen, G.J., Anderson, T.J., Dalrymple-Alford, J.C. (2016). Different PD-MCI criteria and risk of dementia in Parkinson’s disease: Four year longitudinal study. npj Parkinson's Disease, 2, 15027. 10.1038/npjparkd.2015.27

2015

Download Tracking Parkinson's disease over one year with multimodal magnetic resonance imaging in a group of older patients with moderate disease.
Melzer, T.R., Myall, D.J., MacAskill, M.R., Pitcher, T.L., Livingston, L., Watts, R., Keenan, R.J., Dalrymple-Alford, J.C., Anderson, T.J. (2015). Tracking Parkinson's disease over one year with multimodal magnetic resonance imaging in a group of older patients with moderate disease. PLOS ONE, 10, e0143923. 10.1371/journal.pone.0143923

2014

Download Comparing cerebral perfusion in Alzheimer's disease and Parkinson's disease dementia: an ASL-MRI study.
Le Heron, C. J., Wright, S. L., Melzer, T. R., Myall, D. J., MacAskill, M. R., Livingston, L., Keenan, R. J., Watts, R., Dalrymple-Alford, J. C. , Anderson, T.J. (2014). Comparing cerebral perfusion in Alzheimer's disease and Parkinson's disease dementia: an ASL-MRI study.  Journal of Cerebral Blood Flow & Metabolism, 34, 964-970. 10.1038/jcbfm.2014.40
Download Comparison of cognitive and UHDRS measures in monitoring disease progression in Huntington's disease: a 12-month longitudinal study.
Toh, E., MacAskill, M., Dalrymple-Alford, J., Myall, D., Livingston, L., Macleod, S. , Anderson, T. (2014). Comparison of cognitive and UHDRS measures in monitoring disease progression in Huntington's disease: a 12-month longitudinal study.  Translational Neurodegeneration,  3.

2013

Download White matter microstructure deteriorates across cognitive stages in Parkinson disease.
Melzer, T. R., Watts, R., MacAskill, M. R., Pitcher, T. L., Livingston, L., Keenan, R., Dalrymple-Alford, J. C., Anderson, T. J. (2013). White matter microstructure deteriorates across cognitive stages in Parkinson disease. Neurology, 80, 1841-1849. 10.1212/WNL.0b013e3182929f62

2012

Download The influence of motor and cognitive impairment upon visually-guided saccades in Parkinson’s disease.
MacAskill, M. R., Graham, C. F., Pitcher, T. L., Myall, D. J., Livingston, L., van Stockum, S., Dalrymple-Alford, J. C., Anderson, T. J. (2012). The influence of motor and cognitive impairment upon visually-guided saccades in Parkinson’s disease. Neuropsychologia, 50, 3338-3347. 10.1016/j.neuropsychologia.2012.09.025
Download Grey matter atrophy in cognitively impaired Parkinson’s disease.
Melzer, T. R., Watts, R., MacAskill, M. R., Pitcher, T. L., Livingston, L., Keenan, R., Dalrymple-Alford, J. C., Anderson, T. J. (2012). Grey matter atrophy in cognitively impaired Parkinson’s disease. Journal of Neurology, Neurosurgery & Psychiatry, 83(2), 188-194. 10.1186/2047-9158-1-17
Download Reduced striatal volumes in Parkinson’s disease: a magnetic resonance imaging study.
Pitcher, T. L., Melzer, T. R., MacAskill, M. R., Graham, C. F., Livingston, L., Keenan, R. J., Watts, R., Dalrymple-Alford, J. C., Anderson, T. J. (2012). Reduced striatal volumes in Parkinson’s disease: a magnetic resonance imaging study. Translational Neurodegeneration, 1(1), 17. 10.1186/2047-9158-1-17

2011

Download Characterizing mild cognitive impairment in Parkinson’s disease.
Dalrymple-Alford, J. C., Livingston, L., MacAskill, M. R., Graham, C., Melzer, T. R., Porter, R., Watts, R., Anderson, T. J. (2011). Characterizing mild cognitive impairment in Parkinson’s disease. Movement Disorders, 26(4), 629-636. 10.1002/mds.23592
Download Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson’s disease.
Melzer, T. R., Watts, R., MacAskill, M. R., Pearson, J. F., Rüeger, S., Pitcher, T. L., Livingston, L., Graham, C., Keenan, R., Shankaranarayanan, A., Alsop, D. C., Dalrymple-Alford, J. C., Anderson, T. J. (2011). Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson’s disease. Brain,  134(3), 845-855. 10.1093/brain/awq377

2010

Download The MoCA: Well-suited screen for cognitive impairment in Parkinson’s disease.
Dalrymple-Alford, J. C., MacAskill, M. R., Nakas, C. T., Livingston, L., Graham, C., Crucian, G. P., Melzer, T. R., Kirwan, J., Keenan, R., Wells, S., Porter, R. J., Watts, R., Anderson, T.J. (2010). The MoCA: Well-suited screen for cognitive impairment in Parkinson’s disease. Neurology, 75, 1717-1725. 10.1212/WNL.0b013e3181fc29c9

Abstracts and Short papers

2020

Download Neuropsychiatric symptoms are associated with dementia in Parkinson’s disease but not predictive of it.
Horne, K.-L., MacAskill, M. R., Myall, D., Livingston, L., Grenfell, S., Pascoe, M. J., Young, B., Shoorangiz, R., Melzer, T. R., Pitcher, T. L., Anderson, T. J., Dalrymple-Alford, J. C. (2020). Neuropsychiatric symptoms are associated with dementia in Parkinson’s disease but not predictive of it. MedRxiv, 2020, 09, 01, 20186312. https://doi.org/10.1101/2020.09.01.20186312

2016

Horne, K, Myall, DJ, Livingston, L, Grenfell, SF, Melzer, TR, Pitcher, TL, MacAskill, MR, Anderson, TJ, Dalrymple-Alford, JC (2016). Risk of dementia in Parkinson’s disease: Towards optimal short cognitive testing.  Proceedings of the 34th International Winter Conference on Brain Research, 1.
Melzer, TR, Keenan, RJ, Myall, DJ, Kaur, G, Livingston, L, Horne, K, Marsh, S, MacAskill, MR, Dalrymple-Alford, JC, Anderson, TJ (2016). Amyloid imaging and cognition in Parkinson’s disease: Interim report.  Proceedings of the 34th International Winter Conference on Brain Research, 3.

2015

Almuqbel, M, Melzer, TR, Myall, DJ, MacAskill, MR, Livingston, L, Pitcher, TL, Dalrymple-Alford, JC, Anderson, TJ (2015). Longitudinal magnetic resonance spectroscopy in Parkinson’s disease. Proceedings of the 21st Annual Meeting of the Organization for Human Brain Mapping.
Melzer, TR, Myall, DJ, MacAskill, MR, Livingston, L, Pitcher, TL, Watts, R, Keenan, RJ, Dalrymple-Alford, JC, Anderson, TJ (2015). White matter lesions contribute to future dementia in Parkinson’s disease. Proceedings of the 21st Annual Meeting of the Organization for Human Brain Mapping.

2014

Almuqbel, M., Melzer, T., Myall, D., MacAskill, M., Livingston, L., Wood, K., Pitcher, T., Dalrymple-Alford, J. , Anderson, T. (2014). Cognitive status in Parkinsons disease characterised by magnetic resonance spectroscopy.  Proceedings of the International Australasian Winter Conference on Brain Research (AWCBR), Queenstown, New Zealand,  32, 34.
Myall, D., Wood, K., Livingston, L., Pitcher, T., Melzer, T., MacAskill, M., Anderson, T. , Dalrymple-Alford, J. (2014). Individualised medicine: Predicting dementia in Parkinsons disease.  Proceedings of the International Australasian Winter Conference on Brain Research (AWCBR), Queenstown, New Zealand,  32, Abstract 8.1.
Wood, K., Myall, D., Livingston, L., Melzer, T., Pitcher, T., MacAskill, M., Anderson, T. , Dalrymple-Alford, J. (2014). Comparing mild cognitive impairment criteria in Parkinsons disease: influence on dementia onset.  Proceedings of the International Australasian Winter Conference on Brain Research (AWCBR), Queenstown, New Zealand, 32, Abstract 6.4.

2013

Dalrymple-Alford, J. C., Livingston, L., Melzer, T. R., Wood, K., Goh, T. J., Pitcher, T. L., Graham, C. F., Keenan, R. J., MacAskill, M. R. , Anderson, T.J. (2013). Current perspectives on Parkinsons disease: Cognition to the fore.  Proceedings of the 31st Australasian Winter Conference on Brain Research 2013, Queenstown,  Volume 31, Abstract 29.
Dalrymple-Alford, J., McCurrie, C., Anderson, T., Watts, R., MacAskill, M., Pitcher, T., Livingston, L., Keenan, R. , Melzer, T. (2013). Domain specific cognitive dysfunction in Parkinson’s Disease and associated pattern of grey matter atrophy.  Proceedings of the Movement Disorders Society 17th International Congress - Sydney, Abstract 572..
Grenfell, S., Melzer, T. R., Young, B., Wang, A, Livingston, L., Keenan, R. J., MacAskill, M. R., Anderson, T. J. , Dalrymple-Alford, J.C. (2013). Reduced default mode network connectivity and autobiographical memory in mild cognitive impairment.  Proceedings of the 31st Australasian Winter Conference on Brain Research 2013, Queenstown, Volume 31, Abstract 27.
Melzer, T. R., Watts, R., MacAskill, M., Pitcher, T., Livingston, L., Keenan, R., Dalrymple-Alford, J. , Anderson, T. (2013). Serial DTI and cognitive decline in Parkinsons disease. Proceedings of the Movement Disorders Society 17th International Congress, Sydney,  Movement Disorders, 28 Supplement 1, 555.
Toh, E., MacAskill, M., Dalrymple-Alford, J., Myall, D., MacLeod, S., Livingston, L. , Anderson, T. (2013). Progression in cognitive function of Huntington patients relative to controls: a 12 months study. Proceedings of the Movement Disorders Society 17th International Congress, Sydney, Movement Disorders, 28 Supplement 1, Abstract 760 .
Toh, E., MacAskill, M., Dalrymple-Alford, J., Myall, D., MacLeod, S., Livingston, L. , Anderson, T. (2013). Proceedings of the Movement Disorders Society 17th International Congress, Sydney,  Movement Disorders, 28 Supplement 1, Abstract 758.
Wood, K., Livingston, L., Melzer, T. R., Pitcher, T. L., MacAskill, M. R., Anderson, T. J. , Dalrymple-Alford, J.C. (2013). Criteria for Parkinson’s disease with mild cognitive impairment associated with increased progression to dementia.  Proceedings of the 31st Australasian Winter Conference on Brain Research 2013, Queenstown,  Volume 31, 58.

2012

Toh, E., MacAskill, M., Dalrymple-Alford, J., Myall, D., Livingston, L., MacLeod, A. , Anderson, T. (2012). Impairment of implicit prediction in rhythmic saccadic movement in symptomatic huntington patients (Abstract). Journal of Neurology, Neurosurgery, and Psychiatry, 83:Suppl 1, A34. 10.1136/jnnp-2012-303524.104
Toh, E., MacAskill, M., Dalrymple-Alford, J., Myall, D., Livingston, L., Ross, J., Anderson, T. (2012). The effectiveness of cognitive and reflexive saccade measures in discriminating Huntingtons disease from healthy controls (Abstract).  European Journal of Neurology, 19 Suppl 1, Poster 1661. 10.1111/j.1468-1331.2012.03888.x