Prof John Dalrymple-Alford

Professor of Psychology

New Zealand Brain Research Institute, Christchurch

Professor of Psychology

School of Psychology, Speech and Hearing, University of Canterbury, Christchurch

Research interests include neuroscience and neuropsychology, including disorders of memory, neurodegenerative disorders, recovery of function after brain damage; behavioural neuroscience, including animal models of the effects of brain damage in humans, neural transplants, hippocampal system function, enriched environments; and behavioural pharmacology, including effects of drugs and nutritional factors in humans and animals.

  • Alzheimer's disease, Parkinson's disease, Multiple Sclerosis
  • Behavioural pharmacology
  • Enriched environments
  • Hippocampal system function
  • Neural transplants
  • Neuropsychology, including disorders of memory
  • Recovery of function after brain damage.


Link to Professor John Dalrymple-Alford's University of Canterbury page 

Link to Professor John Dalrymple-Alford's Google Scholar page

 

Publications

Provided on request for non-commercial personal use by researchers.

2024

Download Early‐phase amyloid PET reproduces metabolic signatures of cognitive decline in Parkinson's disease.
Aye, W. W., Stark, M. R., Horne, K.-L., Livingston, L., Grenfell, S., Myall, D. J., Pitcher, T.L., Almuqbel, M.M., Keenan, R. J., Meissner, W.G., Dalrymple-Alford, J., Anderson, T.J., Le Heron, C., Melzer, T. R. (2024). Early‐phase amyloid PET reproduces metabolic signatures of cognitive decline in Parkinson's disease. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 16(2), e12601.. 10.1002/dad2.12601
Download Higher Frequency of Stuttered Disfluencies Negatively Affects Communicative Participation in Parkinson's Disease.
Gooch, E., Melzer, T.R., Horne, K.L., Grenfell, S., Livingston, L., Pitcher, T., Dalrymple-Alford, J.C., Anderson, T.J., McAuliffe, M.J., Theys, C. (2024). Higher Frequency of Stuttered Disfluencies Negatively Affects Communicative Participation in Parkinson's Disease. Journal of Speech Language and Hearing Research, 1-12. 10.1044/2024_JSLHR-24-00018
Download Verbal Learning and Memory Deficits across Neurological and Neuropsychiatric Disorders: Insights from an ENIGMA Mega Analysis.
Kennedy, E., Liebel, S.W., Lindsey, H.M, ..., Anderson, T.J, ..., Dalrymple-Alford, J.C, ..., Melzer, T.R., ..., Myall, D.J, ..., Dennis, E.L. (2024). Verbal Learning and Memory Deficits across Neurological and Neuropsychiatric Disorders: Insights from an ENIGMA Mega Analysis. Brain Sciences, 14(7), 669. 10.3390/brainsci14070669
Download Cross-Sectional and Longitudinal Association of Clinical and Neurocognitive Factors With Apathy in Patients With Parkinson Disease.
Le Heron, C., Horne, K. L., MacAskill, M. R., Livingston, L., Melzer, T. R., Myall, D., Pitcher, T., Dalrymple-Alford, J., Anderson, T., Harrison, S. (2024). Cross-Sectional and Longitudinal Association of Clinical and Neurocognitive Factors With Apathy in Patients With Parkinson Disease. Neurology, 102(12), e209301. 10.1212/WNL.0000000000209301
Download A Worldwide Study of White Matter Microstructural Alterations in People Living with Parkinson's Disease.
Owens-Walton, C., Nir, T. M., Al-Bachari, S., Ambrogi, S., Anderson, T. J., Aventurato, I. K., ..., Dalrymple-Alford, J.C, ..., Melzer, T.R, ..., Pitcher, T.L., ..., van der Werf, Y. D. (2024). A Worldwide Study of White Matter Microstructural Alterations in People Living with Parkinson's Disease. medRxiv, 2024-01. 10.1101/2024.01.16.24301235
Download Cholinergic basal forebrain integrity and cognition in Parkinson’s disease: a re-appraisal of MRI evidence.
Slater, N., Melzer, T.R., Myall, D.J., Anderson, T.J., Dalrymple-Alford, J.C. (2024). Cholinergic basal forebrain integrity and cognition in Parkinson’s disease: a re-appraisal of MRI evidence. Movement Disorders, 12, 2155-2172. 10.1002/mds.30023

2023

Download Extracellular vesicle biomarkers for cognitive impairment in Parkinson’s disease.
Blommer, J., Pitcher, T., Mustapic, M., Eren, E., Yao, P. J., Vreones, M. P., Pucha, K. A., Dalrymple-Alford, J., Shoorangiz, R., Meissner, W. G., Anderson, T., Kapogiannis, D. (2023). Extracellular vesicle biomarkers for cognitive impairment in Parkinson’s disease. Brain, 146(1), 195–208. 10.1093/brain/awac258
Dalrymple-Alford, J.C., Anderson, T.J., Melzer, T.R. (2023). Thalamus, thalamocortical networks, and non-motor symptoms in Parkinson’s disease. book chapter in Cerebral Cortex and Thalamus XII.
Download Cyclic Glycine-Proline (cGP) Normalises Insulin-Like Growth Factor-1 (IGF-1) Function: Clinical Significance in the Ageing Brain and in Age-Related Neurological Conditions.
Guan, J., Li, F., Kang, D., Anderson, T., Pitcher, T., Dalrymple-Alford, J., Shorten, P., Singh-Mallah, G. (2023). Cyclic Glycine-Proline (cGP) Normalises Insulin-Like Growth Factor-1 (IGF-1) Function: Clinical Significance in the Ageing Brain and in Age-Related Neurological Conditions. Molecules, 28, 1021. 10.3390/molecules28031021
Download The thalamic reuniens is associated with consolidation of non-spatial memory too.
Hamilton, J. J., Dalrymple-Alford, J. C. (2023). The thalamic reuniens is associated with consolidation of non-spatial memory too. Frontiers in Behavioral Neuroscience, 17, 2023-04. 10.3389/fnbeh.2023.1215625
Download Bridging Big Data: Procedures for Combining Non-equivalent Cognitive Measures from the ENIGMA Consortium.
Kennedy, E., Vadlamani, S., Lindsey, H. M., Lei, P. W., Pugh, M. J., Adamson, M., ... , Anderson, T.J., ... , Dalrymple-Alford, J.C., ... , Melzer, T.R, ... , Myall, D.J., ... , Wilde, E. A. (2023). Bridging Big Data: Procedures for Combining Non-equivalent Cognitive Measures from the ENIGMA Consortium. bioRxiv, 2023-01. 10.1101/2023.01.16.524331
Download Cerebellar Volume and Disease Staging in Parkinson's Disease: An ENIGMA-PD Study.
Kerestes, R., Laansma, M., ..., Anderson, T., ..., Dalrymple-Alford, J., ..., Melzer, T., ..., Pitcher, T., ..., the ENIGMA-Parkinson's Study (2023). Cerebellar Volume and Disease Staging in Parkinson's Disease: An ENIGMA-PD Study. Movement Disorders. 10.1002/mds.29611
Download The New Zealand Parkinson’s Progression Programme.
MacAskill, M. R., Pitcher, T. L., Melzer, T. R., Myall, D. J., Horne, K.-L., Shoorangiz, R., Almuqbel, M. M., Livingston, L., Grenfell, S., Pascoe, M. J., Marshall, E. T., Marsh, S., Perry, S. E., Meissner, W. G., Theys, C., Le Heron, C. J., Keenan, R. J., Dalrymple-Alford, J. C., Anderson, T. J. (2023). The New Zealand Parkinson’s Progression Programme. Journal of the Royal Society of New Zealand, 53, 466-488. 10.1080/03036758.2022.2111448
Download Altered nucleus accumbens functional connectivity precedes apathy in Parkinson’s disease.
Morris, L. A., Harrison, S. J., Melzer, T. R., Dalrymple-Alford, J. C., Anderson, T. J., MacAskill, M. R., Le Heron, C. J. (2023). Altered nucleus accumbens functional connectivity precedes apathy in Parkinson’s disease. Brain, awad113. 10.1093/brain/awad113
Download Neuron arbor geometry is sensitive to the limited-range fractal properties of their dendrites.
Rowland, C., Smith, J. H., Moslehi, S., Harland, B., Dalrymple-Alford, J., Taylor, R. P. (2023). Neuron arbor geometry is sensitive to the limited-range fractal properties of their dendrites. Frontiers in Network Physiology, 3, 1072815. 10.3389/fnetp.2023.1072815

2022

Download Level I PD‐MCI using global cognitive tests and the risk for Parkinson’s disease dementia.
Boel, J. A., Bie, R. M. A., Schmand, B. A., Dalrymple‐Alford, J. C., Marras, C., Adler, C. H., Goldman, J. G., Tröster, A. I., Burn, D. J., Litvan, I., Geurtsen, G. J., the MDS Study Group Mild Cognitive Impairment in Parkinson’s Disease (2022). Level I PD‐MCI using global cognitive tests and the risk for Parkinson’s disease dementia. Movement Disorders Clinical Practice, 9(4), 479-483. 10.1002/mdc3.13451
Download Anterior thalamic nuclei: A critical substrate for non‐spatial paired‐associate memory in rats.
Hamilton, J. J., Dalrymple-Alford, J. C. (2022). Anterior thalamic nuclei: A critical substrate for non‐spatial paired‐associate memory in rats. European Journal of Neuroscience, 56(7), 5014-5032. 10.1111/ejn.15802
Download Reproducibility and repeatability of magnetic resonance imaging in dementia.
Morgan, C.A., Roberts, R.P., Chaffey, T., Tahara-Eckl, L., van der Meer, M., Günther, M., Anderson, T.J., Cutfield, N.J., Dalrymple-Alford, J.C., Kirk, I.J., Addis, D R., Tippett, L.J., Melzer, T.R. (2022). Reproducibility and repeatability of magnetic resonance imaging in dementia. Physica Medica, 101, 8-17. doi.org/10.1016/j.ejmp.2022.06.012
Download Investigating fractal analysis as a diagnostic tool that probes the connectivity of hippocampal neurons.
Rowland, C., Harland, B., Smith, J. H., Moslehi, S., Dalrymple-Alford, J., Taylor, R. P. (2022). Investigating fractal analysis as a diagnostic tool that probes the connectivity of hippocampal neurons. Frontiers in Physiology, 13, 932598. 10.3389/fphys.2022.932598
Download Dementia Prevention Research Clinic: A longitudinal study investigating factors influencing the development of Alzheimer’s disease in Aotearoa.
Tippett, L. J., Cawston, E. E., Morgan, C. A., Melzer, T. R., Brickell, K. L., Ilse, C., Cheung, G., Kirk, I. J., Roberts, R. P., Govender, J., Griner, L., Le Heron, C., Buchanan, S., Port, W., Dudley, M., Anderson, T. J., Williams, J. M., Cutfield, N. J., Dalrymple-Alford, J. C., … the NZ-DPRC. (2022). Dementia Prevention Research Clinic: A longitudinal study investigating factors influencing the development of Alzheimer’s disease in Aotearoa. Journal of the Royal Society of New Zealand. 10.1080/03036758.2022.2098780
Zhao, Y., Laansma, M. A., van Heese, E. M., Owens-Walton, C., Parkes, L. M., Debove, I., Rummel, C., Wiest, R., Cendes, F., Guimaraes, R., Yasuda, C. L., Wang, J.-J., Anderson, T. J., Dalrymple-Alford, J. C., Melzer, T. R., Pitcher, T. L., Schmidt, R., Schwingenschuh, P., Garraux, G., … for the ENIGMA consortium. (2022). Learning interpretable regularized ordinal models from 3D mesh data for neurodegenerative disease staging. In Abdulkadir, Bathula, Dvornek, Habes, Kia, Kumar, & Wolfers (Eds.),. Machine Learning in Clinical Neuroimaging, 13596, 115–124. 10.1007/978-3-031-17899-3_12

2021

Download Anterior thalamic nuclei neurons sustain memory.
Barnett, S. C., Parr-Brownlie, L. C., Perry, B. A. L., Young, C. K., Wicky, H. E., Hughes, S. M., ..., ..., Dalrymple-Alford, J. C. (2021). Anterior thalamic nuclei neurons sustain memory. Current Research in Neurobiology, 2, 100022. 10.1016/j.crneur.2021.100022
Download Automated segmentation of substantia nigra and red nucleus using quantitative susceptibility mapping images: application to Parkinson’s disease.
Basukala, D., Mukundan, R., Lim, A., Hurrell, M. A., Keenan, R. J., Dalrymple-Alford, J. C., Anderson, T. J., Myall, D. J., Melzer, T. R. (2021). Automated segmentation of substantia nigra and red nucleus using quantitative susceptibility mapping images: application to Parkinson’s disease. Computers & Electrical Engineering, 91, 107091. 10.1016/j.compeleceng.2021.107091
Download Higher perceived stress and exacerbated motor symptoms in Parkinson's disease during the COVID-19 lockdown in New Zealand.
Blakemore, R. L., Pascoe, M. J., Horne, K. L., Livingston, L., Young, B. N., Elias, B., Goulden, M., Grenfell, S., Myall, D. J., Pitcher, T. L., Dalrymple-Alford, J. C., Le Heron, C. J., Anderson, T. J., MacAskill, M. R. (2021). Higher perceived stress and exacerbated motor symptoms in Parkinson's disease during the COVID-19 lockdown in New Zealand. The New Zealand Medical Journal, 134, 44-51.
Download Neuropsychiatric symptoms are associated with dementia in Parkinson’s disease but not predictive of it.
Horne, K., MacAskill, M. R., Myall, D. J., Livingston, L., Grenfell, S., Pascoe, M. J., Young, B., Shoorangiz, R., Melzer, T. R., Pitcher, T. L., Anderson, T. J., Dalrymple‐Alford, J. C. (2021). Neuropsychiatric symptoms are associated with dementia in Parkinson’s disease but not predictive of it. Movement Disorders Clinical Practice, 8, 390-399. 10.1002/mdc3.13151
Download International multicenter analysis of brain structure across clinical stages of Parkinson’s disease.
Laansma, M. A., Bright, J. K., Al‐Bachari, S., Anderson, T. J., Ard, T., Assogna, F., Baquero, K. A., Berendse, H. W., Blair, J., Cendes, F., Dalrymple‐Alford, J. C., Bie, R. M. A., Debove, I., Dirkx, M. F., Druzgal, J., Emsley, H. C. A., Garraux, G., Guimarães, R. P., Gutman, B. A., Helmich, R. C., Klein, J. C., Mackay, C. E., McMillan, C. T., Melzer, T. R., Parkes, L. M., Piras, F., Pitcher, T. L., Poston, K. L., Rango, M., Ribeiro, L. F., Rocha, C. S., Rummel, C., Santos, L. S. R., Schmidt, R., Schwingenschuh, P., Spalletta, G., Squarcina, L., Heuvel, O. A., Vriend, C., Wang, J., Weintraub, D., Wiest, R., Yasuda, C. L., Jahanshad, N., Thompson, P. M., Werf, Y. D., The ENIGMA‐Parkinson’s Study. (2021). International multicenter analysis of brain structure across clinical stages of Parkinson’s disease. Movement Disorders , 36, 2583-2594. 10.1002/mds.28706
Download A multi-step model of Parkinson’s disease pathogenesis.
Le Heron, C., MacAskill, M.R., Mason, D., Dalrymple-Alford, J., Anderson, T.J., Pitcher, T., Myall, D.J. (2021). A multi-step model of Parkinson’s disease pathogenesis. Movement Disorders, 36, 2530-2538. 10.1002/mds.28719
Download Spatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia.
Morgan, C. A., Melzer, T. R., Roberts, R. P., Wiebels, K., Mutsaerts, H. J. M. M., Spriggs, M. J., Dalrymple-Alford, J. C., Anderson, T. J., Cutfield, N. J., Deib, G., Pfeuffer, J., Addis, D. R., Kirk, I. J., Tippett, L. J. (2021). Spatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia. Scientific Reports, 11(1), 23325. 10.1038/s41598-021-02313-z
Download Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders.
Nabais, M. F., Laws, S. M., Lin, T., Vallerga, C. L., ..., Anderson, T. J., Bentley, S. R., Dalrymple-Alford, J., Fowder, J., Gratten, J., Halliday, G., Hickie, I. B., Kennedy, M., Lewis, S. J. G., Montgomery, G. W., Pearson, J., Pitcher, T. L., Silburn, P., Zhang, F., Visscher, P. M., Yang, J., Stevenson, A. J., Hillary, R. F., Marioni, R. E., Harris, S. E., Deary, I. J., Jones, A. R., Shatunov, A., Iacoangeli, A., van Rheenen, W., van den Berg, L. H., Shaw, P. J., Shaw, C. E., Morrison, K. E., Al-Chalabi, A., Veldink, J. H., Hannon, E., Mill, J., Wray, N. R., McRae, A. F. (2021). Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biology, 22, 90. 10.1186/s13059-021-02275-5
Download How neurons exploit fractal geometry to optimize their network connectivity.
Smith, J. H., Rowland, C., Harland, B., Moslehi, S., Montgomery, R. D., Schobert, K., Watterson, W. J., Dalrymple-Alford, J. C., Taylor, R. P. (2021). How neurons exploit fractal geometry to optimize their network connectivity. Scientific Reports, 11(1), 1-13. 10.1038/s41598-021-81421-2

2020

Alamri, Y., Dalrymple-Alford, J., MacAskill, M. R., Anderson, T. J. (2020). Exploring eye movements of Parkinson’s disease patients performing the Judgement of Line Orientation test. Journal of Clinical Neuroscience, 76, 183-188. 10.1016/j.jocn.2020.04.031
Download Microstructural integrity of the major nuclei of the thalamus in Parkinson’s disease.
Borlase, N., Myall, D., Melzer, T., Livingston, L., Watts, R., Keenan, R., MacAskill, M., Anderson, T., Dalrymple-Alford, J. (2020). Microstructural integrity of the major nuclei of the thalamus in Parkinson’s disease. bioRxiv, 2020.05.21.1096. 10.1101/2020.05.21.109660
Download Changes of plasma cGP/IGF‐1 molar ratio with age is associated with cognitive status of Parkinson disease.
Fan, D., Pitcher, T. L., Dalrymple-Alford, J., MacAskill, M. R., Anderson, T. J., Guan, J. (2020). Changes of plasma cGP/IGF‐1 molar ratio with age is associated with cognitive status of Parkinson disease. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 12, e12025. 10.1002/dad2.12025
Download Nanopore sequencing of the glucocerebrosidase (GBA) gene in a New Zealand Parkinson's disease cohort.
Graham, O. E., Pitcher, T. L., Liau, Y., Miller, A. L., Dalrymple-Alford, J. C., Anderson, T. J., Kennedy, M. A. (2020). Nanopore sequencing of the glucocerebrosidase (GBA) gene in a New Zealand Parkinson's disease cohort. Parkinsonism & Related Disorders, 70, 36-41. 10.1016/j.parkreldis.2019.11.022
Grasby, K. L. & Jahanshad, N. et al. (2020). The genetic architecture of the human cerebral cortex. Science, 367(6484), eaay6690. 10.1126/science.aay6690
Download Cognitive tests that identify high risk of conversion to dementia in Parkinson's disease.
Myall, D.J., Horne, K., MacAskill, M.R., Livingston, L., Pitcher, T.L., Melzer, T.R., Geurtsen, G.J., Anderson, T.J., Dalrymple-Alford, J.C. (2020). Cognitive tests that identify high risk of conversion to dementia in Parkinson's disease. bioRxiv, 2020.05.31.1268. 10.1101/2020.05.31.126870
Download Positive association of ascorbate and inverse association of urate with cognitive function in people with Parkinson’s disease.
Spencer, E. S., Pitcher, T., Veron, G., Hannam, T., MacAskill, M., Anderson, T., Dalrymple-Alford, J. C., Carr, A. C. (2020). Positive association of ascorbate and inverse association of urate with cognitive function in people with Parkinson’s disease. Antioxidants, 9, 906. 10.3390/antiox9100906
Download Analysis of DNA methylation associates the cystine-glutamate antiporter SLC7A11 with risk of Parkinson’s disease.
Vallerga, C., Zhang, F., Fowdar, J., McRae, A., Qi, T., Nabais, M., Zhang, Q., Kassam, I., Henders, A., Wallace, L., Montgomery, G., Chuang, Y-H., Horvath, S., Ritz, B., Halliday, G., Hickie, I., Kwok, J., Pearson, J., Pitcher, T., Kennedy, M., Bentley, S., Silburn, P., Yang, J., Wray, N., Lewis, S., Anderson, T., Dalrymple-Alford, J., Mellick, G., Visscher, P., Gratten, J. (2020). Analysis of DNA methylation associates the cystine-glutamate antiporter SLC7A11 with risk of Parkinson’s disease. Nature Communications , 11 (1238), 1-10. 10.1038/s41467-020-15065-7

2019

Blauwendraat, C., Heilbron, K., Vallerga, C. L., Bandres‐Ciga, S., von Coelln, R., Pihlstrøm, L., Siitonen, A., International Parkinson's Disease Genomics Consortium (2019). Parkinson’s disease age at onset genome‐wide association study: Defining heritability, genetic loci, and α‐synuclein mechanisms. Movement Disorders, 34(6), 866-875. 10.1002/mds.27659
Chundru, V. K., Marioni, R. E., Prendergast, J. G. D., Vallerga, C. L., Lin, T., Beveridge, A. J., SGPD Consortium,... Visscher, P. M., McRae, A. F. (2019). Examining the impact of imputation errors on fine-mapping using DNA methylation QTL as a model trait. Genetics. 10.1534/genetics.118.301861
Download Risk of Parkinson’s disease dementia related to level I MDS PD-MCI.
Hoogland, J., Boel, J. A., de Bie, R. M. A., Schmand, B. A., Geskus, R. B., Dalrymple-Alford, J. C., … on behalf of the MDS Study Group “Validation of Mild Cognitive Impairment in Parkinson Disease”. (2019). Risk of Parkinson’s disease dementia related to level I MDS PD-MCI. Movement Disorders. 10.1002/mds.27617
Download Beta amyloid deposition is not associated with cognitive impairment in Parkinson’s disease.
Melzer, T. R., Stark, M. R., Keenan, R. J., Myall, D. J., MacAskill, M. R., Pitcher, T. L., Livingston, L., Grenfell, S., Horne, K., Young, B., Pascoe, M., Almuqbel, M. A., Wang, J., Marsh, S., Miller, D. H., Dalrymple-Alford, J. C., Anderson, T. J. (2019). Beta amyloid deposition is not associated with cognitive impairment in Parkinson’s disease. Frontiers in Neurology, 10, 391. 10.3389/fneur.2019.00391
Download Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.
Nalls, M. A., Blauwendraat, C., Vallerga, C. L., Heilbron, K., Bandres-Ciga, S., Chang, D., and the System Genomics of Parkinson’s Disease Consortium and the International Parkinson’s Disease Genomics Consortium (2019). Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. The Lancet Neurology, 18(12), 1091-1102. 10.1016/S1474-4422(19)30320-5
Download Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability.
Reynolds, R. H., Botía, J., Nalls, M. A., International Parkinson’s Disease Genomics Consortium (IPDGC), System Genomics of Parkinson’s Disease (SGPD), Hardy, J., Taliun, S. A. G., Ryten, M. (2019). Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability. npj Parkinson's Disease, 5, 1-14. 10.1038/s41531-019-0076-6
Ulrich, K., Spriggs, M. J., Abraham, W. C., Dalrymple‐Alford, J. C., McNaughton, N. (2019). Environmental enrichment increases prefrontal EEG power and synchrony with the hippocampus in rats with anterior thalamus lesions. Hippocampus, 29, 128-140. 10.1002/hipo.23022

2018

Barnett, S. C., Perry, B. A. L., Dalrymple‐Alford, J. C., Parr‐Brownlie, L. C. (2018). Optogenetic stimulation: Understanding memory and treating deficits. Hippocampus, 28, 457-470. 10.1002/hipo.22960
Download Functional connectivity alterations reveal complex mechanisms based on clinical and radiological status in mild relapsing remitting multiple sclerosis.
Castellazzi, G., Debernard, L., Melzer, T. R., Dalrymple-Alford, J. C., D’Angelo, E., Miller, D. H., Wheeler-Kingshott, C. A., Mason, D. F. (2018). Functional connectivity alterations reveal complex mechanisms based on clinical and radiological status in mild relapsing remitting multiple sclerosis. Frontiers in Neurology, 9, 690. 10.3389/fneur.2018.00690
Download Supplementation of blackcurrant anthocyanins increased cyclic glycine-proline in the cerebrospinal fluid of Parkinson patients: potential treatment to improve insulin-like growth factor-1 function.
Fan, D., Alamri, Y., Liu, K., MacAskill, M., Harris, P., Brimble, M., Dalrymple-Alford, J., Prickett, T., Menzies, O., Laurenson, A., Anderson, T., Guan, J.   (2018). Supplementation of blackcurrant anthocyanins increased cyclic glycine-proline in the cerebrospinal fluid of Parkinson patients: potential treatment to improve insulin-like growth factor-1 function. Nutrients, 10, 714. 10.3390/nu10060714
Download The genetic architecture of the human cerebral cortex.
Grasby, Katrina L., Jahanshad, Neda, Painter, Jodie N., ..., Melzer, Tracy R., ..., Pitcher, Toni L., ..., Anderson, Tim J., ..., Dalrymple-Alford, John C., ..., on behalf of the Enhancing NeuroImaging Genetics through Meta-Analysis Consortium - Genetics working group (2018). The genetic architecture of the human cerebral cortex. BioRxiv, 399402. 10.1101/399402
Download Detecting mild cognitive deficits in Parkinson's disease: comparison of neuropsychological tests.
Hoogland, J., van Wanrooij, L. L., Boel, J. A., Goldman, J. G., Stebbins, G. T., Dalrymple‐Alford, J. C., ..., & Mollenhauer, B. (2018). Detecting mild cognitive deficits in Parkinson's disease: comparison of neuropsychological tests. Movement Disorders. 10.1002/mds.110
Download The Symbol-Digit Modalities Test in mild cognitive impairment: evidence from Parkinson's disease patients.
Pascoe, M. J., Alamri, Y., Dalrymple-Alford, J. C., Anderson, T. J., MacAskill, M. R. (2018). The Symbol-Digit Modalities Test in mild cognitive impairment: evidence from Parkinson's disease patients. European Neurology, 79, 206-210. 10.1159/000485669
Download Anterior thalamic nuclei lesions have a greater impact than mammillothalamic tract lesions on the extended hippocampal system.
Perry, B. A. L., Mercer, S. A., Barnett, S. C., Lee, J., Dalrymple-Alford, J. C. (2018). Anterior thalamic nuclei lesions have a greater impact than mammillothalamic tract lesions on the extended hippocampal system. Hippocampus, 28, 121-135. 10.1002/hipo.22815
Download Parkinson’s disease across ethnicities: a nation-wide study in New Zealand.
Pitcher, T. L., Myall, D. J., Pearson, J. F., Lacey, C. J., Dalrymple-Alford, J. C., Anderson, T. J., MacAskill, M. R. (2018). Parkinson’s disease across ethnicities: a nation-wide study in New Zealand. Movement Disorders, 33, 1440-1448. 10.1002/mds.27389
Download Environmental enrichment elicits a transient rise of bioactive C-type natriuretic peptide in young but not aged rats.
Rapley, S., Prickett, T., Dalrymple-Alford, J., Espiner, E. (2018). Environmental enrichment elicits a transient rise of bioactive C-type natriuretic peptide in young but not aged rats. Frontiers in Behavioral Neuroscience, 12, 142. 10.3389/fnbeh.2018.00142

2017

Download Errors on the MoCA's animal-naming: findings from Parkinson’s disease patients.
Alamri, Y., Anderson, T., Dalrymple-Alford, J., MacAskill, M. (2017). Errors on the MoCA's animal-naming: findings from Parkinson’s disease patients. International Psychogeriatrics, 1-2. 10.1017/S1041610217000345
Download Construction of joint confidence regions for the optimal true class fractions of Receiver Operating Characteristic (ROC) surfaces and manifolds.
Bantis, L. E., Nakas, C. T., Reiser, B., Myall, D., Dalrymple-Alford, J. C. (2017). Construction of joint confidence regions for the optimal true class fractions of Receiver Operating Characteristic (ROC) surfaces and manifolds. Statistical Methods in Medical Research, 26, 1429-1442. 10.1177/0962280215581694
Download Mild cognitive impairment as a risk factor for Parkinson’s disease dementia.
Hoogland, J., Boel, J. A., de Bie, R. M. A., Geskus, R. B., Schmand, B. A., Dalrymple-Alford, J. C., Marras, C., Adler, C. H., Goldman, J. G., Tröster, A. I., Burn, D. J., Litvan, I., Geurtsen, G. J., MDS Study Group “Validation of Mild Cognitive Impairment in Parkinson Disease”. (2017). Mild cognitive impairment as a risk factor for Parkinson’s disease dementia. Movement Disorders, 32, 1056-1065. 10.1002/mds.27002
Download Caregiver burden is increased in Parkinson’s disease with mild cognitive impairment (PD-MCI).
Jones, A. J., Kuijer, R. G., Livingston, L., Myall, D., Horne, K., MacAskill, M., Pitcher, T., Barrett, P. T., Anderson, T. J., Dalrymple-Alford, J. C. (2017). Caregiver burden is increased in Parkinson’s disease with mild cognitive impairment (PD-MCI). Translational Neurodegeneration, 6(17). 10.1186/s40035-017-0085-5
Download Parkinson's in the oldest old: Impact on estimates of future disease burden.
Myall, D.J., Pitcher, T.L., Pearson, J.F., Dalrymple-Alford, J.C., Anderson, T.J., MacAskill, M.R. (2017). Parkinson's in the oldest old: Impact on estimates of future disease burden. Parkinsonism and Related Disorders, 42, 78-84. 10.1016/j.parkreldis.2017.06.018

2016

Download Metabolite ratios in the posterior cingulate cortex do not track cognitive decline in Parkinson's disease in a clinical setting.
Almuqbel, M., Melzer, T.R., Myall, D.J., MacAskill, M.R., Pitcher, T.L., Livingston, L., Wood, K., Keenan, R.J., Dalrymple-Alford, J.C., Anderson, T.J. (2016). Metabolite ratios in the posterior cingulate cortex do not track cognitive decline in Parkinson's disease in a clinical setting. Parkinsonism & Related Disorders, 22, 54-61. 10.1016/j.parkreldis.2015.11.008
Download Attention lapses and microsleeps during tracking, psychomotor vigilance, and dual tasks.
Buckley, R. J., Helton, W. S., Innes, C. R., Dalrymple-Alford, J. C., Jones, R. D. (2016). Attention lapses and microsleeps during tracking, psychomotor vigilance, and dual tasks. Consciousness and Cognition, 45, 174-183. 10.1016/j.concog.2016.09.002
Download α-synuclein genetic variability: A biomarker for dementia in Parkinson's disease.
Guella, I., Evans, D. M., Szu-Tu, C., Nosova, E., Bortnick, S. F., SNCA Cognition Study Group, Goldman, J. G., Dalrymple-Alford, J., Geurtsen, G. J., Litvan, I., Ross, O. A., Middleton, L. T., Parkkinen, L., Farrer, M. J. (2016). α-synuclein genetic variability: A biomarker for dementia in Parkinson's disease. Annals of Neurology, 79, 991-999. 10.1002/ana.24664
Download Acute tryptophan depletion and Lewy body dementias.
Mace, J. L., Porter, R. J., Dalrymple-Alford, J. C., Collins, C., Anderson, T. J. (2016). Acute tryptophan depletion and Lewy body dementias. International Psychogeriatrics, 1-5. 10.1017/S1041610216000284
Download Comprehensive clinical assessment of home-based older persons within New Zealand: an epidemiological profile of a national cross-section.
Schluter, P. J., Ahuriri-Driscoll, A., Anderson, T. J., Beere, P., Brown, J., Dalrymple-Alford, J., David, T., Davidson, A., Gillon, D. A., Hirdes, J., Keeling, S., Kingham, S., Lacey, C., Menclova, A. K., Millar, N., Mor, V., Jamieson, H. A. (2016). Comprehensive clinical assessment of home-based older persons within New Zealand: an epidemiological profile of a national cross-section. Australian and New Zealand Journal of Public Health. 10.1111/1753-6405.12525
Download Different PD-MCI criteria and risk of dementia in Parkinson’s disease: Four year longitudinal study.
Wood, K., Myall, D.J., Livingston, L., Melzer, T.R., Pitcher, T.L., MacAskill, M.R., Geurtsen, G.J., Anderson, T.J., Dalrymple-Alford, J.C. (2016). Different PD-MCI criteria and risk of dementia in Parkinson’s disease: Four year longitudinal study. npj Parkinson's Disease, 2, 15027. 10.1038/npjparkd.2015.27

2015

Download Anterior thalamic nuclei lesions and recovery of function: Relevance to cognitive thalamus.
Dalrymple-Alford, JC, Harland, B, Loukavenko, EA, Perry, B, Mercer, S, Collings, DA, Ulrich, K, Abraham, WC, McNaughton, N, Wolff, M. (2015). Anterior thalamic nuclei lesions and recovery of function: Relevance to cognitive thalamus. Neuroscience and Biobehavioral Reviews, 54, 145-160. 10.1016/j.neubiorev.2014.12.007
Download Deep grey matter MRI abnormalities and cognitive function in relapsing-remitting multiple sclerosis.
Debernard, L., Melzer, T. R., Alla, S., Eagle, J., Van Stockum, S., Graham, C., Osborne, J. R., Dalrymple-Alford, J. C., Miller, D. H., Mason, D. F. (2015). Deep grey matter MRI abnormalities and cognitive function in relapsing-remitting multiple sclerosis. Psychiatry Research: Neuroimaging. 10.1016/j.pscychresns.2015.10.00
Download Prediction of driving ability: Are we building valid models?
Hoggarth, PA, Innes, CR, Dalrymple-Alford, JC, Jones, RD. (2015). Prediction of driving ability: Are we building valid models? Accident Analysis and Prevention, 77C, 29-34. 0.1016/j.aap.2015.01.013
Download Impaired spatial working memory after anterior thalamic lesions: Recovery with cerebrolysin and enrichment.
Loukavenko, E.A., Wolff, M., Poirier, G. L., Dalrymple-Alford, J.C. (2015). Impaired spatial working memory after anterior thalamic lesions: Recovery with cerebrolysin and enrichment. Brain Structure & Function. 10.1007/s00429-015-1015-x
Download Tracking Parkinson's disease over one year with multimodal magnetic resonance imaging in a group of older patients with moderate disease.
Melzer, T.R., Myall, D.J., MacAskill, M.R., Pitcher, T.L., Livingston, L., Watts, R., Keenan, R.J., Dalrymple-Alford, J.C., Anderson, T.J. (2015). Tracking Parkinson's disease over one year with multimodal magnetic resonance imaging in a group of older patients with moderate disease. PLOS ONE, 10, e0143923. 10.1371/journal.pone.0143923

2014

Download Reduced grey matter perfusion without volume loss in early relapsing-remitting multiple sclerosis.
Debernard, L., Melzer, T. R., Van Stockum, S., Graham, C., Wheeler-Kingshott, C. A., Dalrymple-Alford, J. C., Miller, D. H. , Mason, D.F. (2014). Reduced grey matter perfusion without volume loss in early relapsing-remitting multiple sclerosis. Journal of Neurology Neurosurgery and Psychiatry, 85. 10.1136/jnnp-2013-305612
Download C-type natriuretic peptide in Parkinson's disease: reduced secretion and response to deprenyl.
Espiner, E. A., Dalrymple-Alford, J. C., Prickett, T. C. R., Alamri, Y. , Anderson, T.J. (2014). C-type natriuretic peptide in Parkinson's disease: reduced secretion and response to deprenyl. Journal of Neural Transmission, 121(4), 371-378. 10.1007/s00702-013-1123-9
Download Parkinson’s Disease Mild Cognitive Impairment: Application and Validation of the Criteria.
Geurtsen, GJ, Hoogland, J, Goldman, JG, Schmand, BA, Tröster, AI, Burn, DJ, Litvan, I, on behalf of the MDS Study group on the validation of PD-MCI criteria. (2014). Parkinson’s Disease Mild Cognitive Impairment: Application and Validation of the Criteria. Journal of Parkinson’s Disease, 4, 131-7. 10.3233/JPD-130304
Download Anterior thalamic lesions reduce spine density in both hippocampal CA1 and retrosplenial cortex, but enrichment rescues CA1 spines only.
Harland, BC, Collings, DA, McNaughton, N, Abraham, WC, Dalrymple-Alford, JC (2014). Anterior thalamic lesions reduce spine density in both hippocampal CA1 and retrosplenial cortex, but enrichment rescues CA1 spines only. Hippocampus, 24(10), 1232-47. 10.1002/hipo.22309
Download Comparing cerebral perfusion in Alzheimer's disease and Parkinson's disease dementia: an ASL-MRI study.
Le Heron, C. J., Wright, S. L., Melzer, T. R., Myall, D. J., MacAskill, M. R., Livingston, L., Keenan, R. J., Watts, R., Dalrymple-Alford, J. C. , Anderson, T.J. (2014). Comparing cerebral perfusion in Alzheimer's disease and Parkinson's disease dementia: an ASL-MRI study.  Journal of Cerebral Blood Flow & Metabolism, 34, 964-970. 10.1038/jcbfm.2014.40
Download Comparison of cognitive and UHDRS measures in monitoring disease progression in Huntington's disease: a 12-month longitudinal study.
Toh, E., MacAskill, M., Dalrymple-Alford, J., Myall, D., Livingston, L., Macleod, S. , Anderson, T. (2014). Comparison of cognitive and UHDRS measures in monitoring disease progression in Huntington's disease: a 12-month longitudinal study.  Translational Neurodegeneration,  3.
Download Effects of thalamic lesions on repeated relearning of a spatial working memory task.
Ulrich, K, Aitken, PN, Abraham, WC, Dalrymple-Alford, JC and McNaughton, N (2014). Effects of thalamic lesions on repeated relearning of a spatial working memory task. Behavioural Brain Research, 261, 56-59. 10.1016/j.bbr.2013.12.002

2013

Download The reuniens and rhomboid nuclei: neuroanatomy, electrophysiological characteristics and behavioral implications.
Cassel, J., Pereira de Vasconcelos, A., Loureiro, M., Cholvin, T., Dalrymple-Alford, J. C., Vertes, R.P. (2013). The reuniens and rhomboid nuclei: neuroanatomy, electrophysiological characteristics and behavioral implications. Progress in Neurobiology, 111, 34-52. 10.1016/j.pneurobio.2013.08.006
Download A role for anterior thalamic nuclei in affective cognition: interaction with environmental conditions.
Dupire, A., Kant, P., Mons, N., Marchand, A. R., Coutureau, E., Dalrymple-Alford, J., Wolff, M. (2013). A role for anterior thalamic nuclei in affective cognition: interaction with environmental conditions.  Hippocampus,  23, 392-404. 10.1002/hipo.22098
Download Prospective study of healthy older drivers: No increase in crash involvement or traffic citations at 24 months following a failed on-road assessment.
Hoggarth, P., Innes, C., Dalrymple-Alford, J., Jones, R. (2013). Prospective study of healthy older drivers: No increase in crash involvement or traffic citations at 24 months following a failed on-road assessment.  Transportation Research Part F: Traffic Psychology and Behaviour,  16, 73-80. 10.1016/j.trf.2012.08.012
Download Predicting on-road assessment pass and fail outcome in older drivers with cognitive impairment using a battery of computerized sensory-motor and cognitive tests.
Hoggarth, P., Innes, C., Dalrymple-Alford, J., Jones, R. (2013). Predicting on-road assessment pass and fail outcome in older drivers with cognitive impairment using a battery of computerized sensory-motor and cognitive tests.  Journal of the American Geriatrics Society, 61, 2192-2198.
Download White matter microstructure deteriorates across cognitive stages in Parkinson disease.
Melzer, T. R., Watts, R., MacAskill, M. R., Pitcher, T. L., Livingston, L., Keenan, R., Dalrymple-Alford, J. C., Anderson, T. J. (2013). White matter microstructure deteriorates across cognitive stages in Parkinson disease. Neurology, 80, 1841-1849. 10.1212/WNL.0b013e3182929f62
Download Lesions of the anterior thalamic nuclei and intralaminar thalamic nuclei: place and visual discrimination learning in the water maze.
Moreau, P., Tsenkina, Y., Lecourtier, L., Lopez, J., Cosquer, B., Wolff, M., Dalrymple-Alford, J. , Cassel, J. (2013). Lesions of the anterior thalamic nuclei and intralaminar thalamic nuclei: place and visual discrimination learning in the water maze.  Brain Structure and Function, 218, 657-667. 10.1007/s00429-012-0419-0
Download Generalization of Youden index for multiple-class classification problems applied to the assessment of externally validated cognition in Parkinson’s disease screening.
Nakas, C. T., Dalrymple-Alford, J. C., Anderson, T. J., Alonzo, T.A. (2013). Generalization of Youden index for multiple-class classification problems applied to the assessment of externally validated cognition in Parkinson’s disease screening. Statistics in Medicine, 32(6), 995-1003. 10.1002/sim.5592
Download Effects of thalamic lesions on repeated relearning of a spatial working memory task.
Ulrich, K., Aitken, P. N., Abraham, W. C., Dalrymple-Alford, J. C., McNaughton, N. (2013). Effects of thalamic lesions on repeated relearning of a spatial working memory task. Behavioural Brain Research,  261C, 56-59. 10.1016/j.bbr.2013.12.002

2012

Download The influence of motor and cognitive impairment upon visually-guided saccades in Parkinson’s disease.
MacAskill, M. R., Graham, C. F., Pitcher, T. L., Myall, D. J., Livingston, L., van Stockum, S., Dalrymple-Alford, J. C., Anderson, T. J. (2012). The influence of motor and cognitive impairment upon visually-guided saccades in Parkinson’s disease. Neuropsychologia, 50, 3338-3347. 10.1016/j.neuropsychologia.2012.09.025
Download Grey matter atrophy in cognitively impaired Parkinson’s disease.
Melzer, T. R., Watts, R., MacAskill, M. R., Pitcher, T. L., Livingston, L., Keenan, R., Dalrymple-Alford, J. C., Anderson, T. J. (2012). Grey matter atrophy in cognitively impaired Parkinson’s disease. Journal of Neurology, Neurosurgery & Psychiatry, 83(2), 188-194. 10.1186/2047-9158-1-17
Download Reduced striatal volumes in Parkinson’s disease: a magnetic resonance imaging study.
Pitcher, T. L., Melzer, T. R., MacAskill, M. R., Graham, C. F., Livingston, L., Keenan, R. J., Watts, R., Dalrymple-Alford, J. C., Anderson, T. J. (2012). Reduced striatal volumes in Parkinson’s disease: a magnetic resonance imaging study. Translational Neurodegeneration, 1(1), 17. 10.1186/2047-9158-1-17

2011

Download Characterizing mild cognitive impairment in Parkinson’s disease.
Dalrymple-Alford, J. C., Livingston, L., MacAskill, M. R., Graham, C., Melzer, T. R., Porter, R., Watts, R., Anderson, T. J. (2011). Characterizing mild cognitive impairment in Parkinson’s disease. Movement Disorders, 26(4), 629-636. 10.1002/mds.23592
Download Task-dependent differences in corticobulbar excitability of the submental motor projections: Implications for neural control of swallowing.
Doeltgen, S. H., Ridding, M. C., Dalrymple-Alford, J., Huckabee, M. (2011). Task-dependent differences in corticobulbar excitability of the submental motor projections: Implications for neural control of swallowing.  Brain Research Bulletin,  84, 88-93.
Download Assessment of older drivers in New Zealand: the current system, research, and recommendations.
Hoggarth, P., Innes, C., Dalrymple-Alford, J., Croucher, M., Severinsen, J., Gray, J., Hampton, J., Oxley, J., Brook, B., Abernethy, P., Jones, R. (2011). Assessment of older drivers in New Zealand: the current system, research, and recommendations. Australasian Journal of Ageing, 30, 148-155. 10.1111/j.1741-6612.2010.00478.x
Download Validity evaluation of a spatial memory task in virtual environments.
Koenig, S., Crucian, G., Dünser, A., Bartneck, C., Dalrymple-Alford, J. (2011). Validity evaluation of a spatial memory task in virtual environments. International Journal of Design and Innovation Research, 6, 1-13.
Download The effects of acute tryptophan depletion on neuropsychological function, mood and movement in the healthy elderly.
Mace, J. L., Porter, R. J., Dalrymple-Alford, J. C., Wesnes, K. A., Anderson, T.J. (2011). The effects of acute tryptophan depletion on neuropsychological function, mood and movement in the healthy elderly.  Journal of Psychopharmacology,  25, 1337-1343. 10.1177/0269881110389094
Download Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson’s disease.
Melzer, T. R., Watts, R., MacAskill, M. R., Pearson, J. F., Rüeger, S., Pitcher, T. L., Livingston, L., Graham, C., Keenan, R., Shankaranarayanan, A., Alsop, D. C., Dalrymple-Alford, J. C., Anderson, T. J. (2011). Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson’s disease. Brain,  134(3), 845-855. 10.1093/brain/awq377

2010

Download Different lip asymmetry in adults who stutter: Electromyographic evidence during speech and non-speech.
Choo, A., Robb, M., Dalrymple-Alford, J., Huckabee, M., O’Beirne, G. (2010). Different lip asymmetry in adults who stutter: Electromyographic evidence during speech and non-speech.  Folia Phoniatrica et Logopaedica,  62, 143 “147.. 10.1159%2F000287213
Download The MoCA: Well-suited screen for cognitive impairment in Parkinson’s disease.
Dalrymple-Alford, J. C., MacAskill, M. R., Nakas, C. T., Livingston, L., Graham, C., Crucian, G. P., Melzer, T. R., Kirwan, J., Keenan, R., Wells, S., Porter, R. J., Watts, R., Anderson, T.J. (2010). The MoCA: Well-suited screen for cognitive impairment in Parkinson’s disease. Neurology, 75, 1717-1725. 10.1212/WNL.0b013e3181fc29c9
Download Differential Effects of Neuromuscular Electrical Stimulation Parameters on Submental Motor Evoked Potentials.
Doeltgen, S. H., Dalrymple-Alford, J., Ridding, M. C., Huckabee, M. (2010). Differential Effects of Neuromuscular Electrical Stimulation Parameters on Submental Motor Evoked Potentials. Neurorehabilitation and Neural Repair,  24, 519-527. 10.1177/1545968309360417
Download Comparison of a linear and non-linear model for using sensory-motor, cognitive, personality and demographic data to predict driving ability in healthy older adults.
Hoggarth, P. A., Innes, C. R. H., Dalrymple-Alford, J. C., Severinsen, J. E., Jones, R.D. (2010). Comparison of a linear and non-linear model for using sensory-motor, cognitive, personality and demographic data to predict driving ability in healthy older adults.  Accident Analysis and Prevention,  42, 1759 - 1768. 10.1016/j.aap.2010.04.017
Download The effects of acute tryptophan depletion on neuropsychological function, mood and movement in the healthy elderly.
Mace, J. L., Porter, R. J., Dalrymple-Alford, J. C., Wesnes, K. A., Anderson, T.J. (2010). The effects of acute tryptophan depletion on neuropsychological function, mood and movement in the healthy elderly.  Journal of Psychopharmacology,  24(10), 1465 - 1472. 10.1177/0269881110389094
Download Effects of acute tryptophan depletion on mood in patients with Parkinson's disease and the healthy elderly.
Mace, J. L., Porter, R. P., Dalrymple-Alford, J., Anderson, T.J. (2010). Effects of acute tryptophan depletion on mood in patients with Parkinson's disease and the healthy elderly.  Journal of Psychopharmacology,  24, 615-619. 10.1177/0269881109105721
Download Characteristics of executive function impairment in Parkinson’s disease patients without dementia.
McKinlay, A., Grace, R. C., Dalrymple-Alford, J. C., Roger, D. (2010). Characteristics of executive function impairment in Parkinson’s disease patients without dementia.  Journal of the International Neuropsychological Society,  16, 268-277. 10.1017/S1355617709991299
Download Sensitivity to genuine versus posed emotion specified in facial displays.
McLellan, T., Johnston, L., Dalrymple-Alford, J., Porter, R. (2010). Sensitivity to genuine versus posed emotion specified in facial displays.  Cognition and Emotion,  24, 1277-1292. 10.1080/02699930903306181

2009

Download Test-retest reliability of motor evoked potentials (MEPs) at the submental muscle group during volitional swallowing.
Doeltgen, S. H., Ridding, M. C., O'Beirne, G. A., Dalrymple-Alford, J., Huckabee, M. (2009). Test-retest reliability of motor evoked potentials (MEPs) at the submental muscle group during volitional swallowing.  Journal of Neuroscience Methods,  178, 134-137. 10.1016/j.jneumeth.2008.12.005
Download Performance in normal subjects on a novel battery of driving-related sensory-motor and cognitive tests.
Innes, C. R. H., Jones, R. D., Anderson, T. J., Hollobon, S. G., Dalrymple-Alford, J.C. (2009). Performance in normal subjects on a novel battery of driving-related sensory-motor and cognitive tests.  Behavior Research Methods,  42(1), 284-294. 10.3758/BRM.41.2.284
Download Virtual reality rehabilitation of spatial abilities after brain damage.
Koenig, S. T., Crucian, G. P., Dalrymple-Alford, J. C., Dünser, A. (2009). Virtual reality rehabilitation of spatial abilities after brain damage. Studies in Health Technology and Informatics, 144, 105-107.
Download The intralaminar thalamic nuclei contribute to remote spatial memory.
Lopez, J., Wolff, M., Lecourtier, L., Cosquer, B., Bontempi, B., Dalrymple-Alford, J., Cassel, J. (2009). The intralaminar thalamic nuclei contribute to remote spatial memory.  Journal of Neuroscience, 29(10), 3302-3306. 10.1523/JNEUROSCI.5576-08.2009
Download Effects of acute tryptophan depletion on neuropsychological and motor function in Parkinson’s disease.
Mace, J. L., Porter, R. J., Dalrymple-Alford, J. C., Wesnes, K. A., Anderson, T.J. (2009). Effects of acute tryptophan depletion on neuropsychological and motor function in Parkinson’s disease.  Journal of Psychopharmacology,  00(00), 1-8. 10.1177/0269881109105721
Download The effect of attentional set-shifting, working memory and processing speed on pragmatic language functioning in Parkinson's disease.
McKinlay, A., Dalrymple-Alford, J. C., Grace, R. C., Roger, D. (2009). The effect of attentional set-shifting, working memory and processing speed on pragmatic language functioning in Parkinson's disease.  European Journal of Cognitive Psychology,  21(2), 330-346. 10.1080/09541440802281266
Download Cognitive characteristics associated with mild cognitive impairment in Parkinson’s disease.
McKinlay, A., Grace, R. C., Dalrymple-Alford, J. C., Roger, D. (2009). Cognitive characteristics associated with mild cognitive impairment in Parkinson’s disease.  Dementia and Geriatric Cognitive Disorders,  289(2), 121-129. 10.1159/000235247
Download Assessing cognitive impairment in Parkinson's disease: A comparison of two tower tasks.
McKinlay, A., Grace, R. C., Kaller, C. P., Dalrymple-Alford, J. C., Anderson, T. J., Fink, J., Roger, D. (2009). Assessing cognitive impairment in Parkinson's disease: A comparison of two tower tasks.  Applied Neuropsychology,  16, 177-185. 10.1080/09084280903098661

2008

Download Coexisting cholinergic and parahippocampal degeneration: a key to memory loss in dementia and a challenge for transgenic models?
Cassel, J., Mathis, C., Majchrzak, M., Moreau, P., Dalrymple-Alford, J.C. (2008). Coexisting cholinergic and parahippocampal degeneration: a key to memory loss in dementia and a challenge for transgenic models?  Neurodegenerative Diseases,  5(5), 304-317. 10.1159%2F000135615
Download Multivariate analysis of diffusion tensor imaging data improves the detection of microstructural damage in young professional boxers.
Chappell, M. H., Brown, J. A., Dalrymple-Alford, J. C., Ulug, A. M., Watts, R. (2008). Multivariate analysis of diffusion tensor imaging data improves the detection of microstructural damage in young professional boxers.  Magnetic Resonance Imaging, 26(10), 1398-1405. 10.1016/j.mri.2008.04.004
Download A profile of neuropsychiatric problems and their relationship to quality of life for Parkinson’s disease patients without dementia.
McKinlay, A., Grace, R. C., Dalrymple-Alford, J. C., Anderson, T., Fink, J., Roger, D. (2008). A profile of neuropsychiatric problems and their relationship to quality of life for Parkinson’s disease patients without dementia.  Parkinsonism & Related Disorders,  14(1), 37-42. 10.1016/j.parkreldis.2007.05.009
Download Neuropsychiatric problems in Parkinson’s disease: Comparisons between self and significant other report.
McKinlay, A., Grace, R. C., Dalrymple-Alford, J. C., Anderson, T., Fink, J., Roger, D. (2008). Neuropsychiatric problems in Parkinson’s disease: Comparisons between self and significant other report. Aging and Mental Health, 12, 647-653. 10.1080/13607860802343225
Download The accuracy of the Unified Parkinson's Disease Rating Scale (UPDRS-Section 1) as a screening measure for depression.
McKinlay, A., Grace, R., Dalrymple-Alford, J., Anderson, T., Fink, J., Roger, D. (2008). The accuracy of the Unified Parkinson's Disease Rating Scale (UPDRS-Section 1) as a screening measure for depression.  Parkinsonism and Related Disorders,  14(2), 170-172. 10.1016/j.parkreldis.2007.03.002
Download Planning in Parkinson's disease: A matter of problem structure?
McKinlay, A., Kaller, C. P., Grace, R. C., Dalrymple-Alford, J. C., Anderson, T. J., Fink, J., Roger, D. (2008). Planning in Parkinson's disease: A matter of problem structure? Neuropsychologia,  46, 384-389. 10.1016/j.neuropsychologia.2007.08.018
Download The recognition of facial expressions of emotion in Alzheimer's disease: A review of findings.
McLellan, T., Johnston, L., Dalrymple-Alford, J., Porter, P. (2008). The recognition of facial expressions of emotion in Alzheimer's disease: A review of findings.  Acta Neuropsychiatrica,  20(5), 236-250. 10.1111/j.1601-5215.2008.00315.x
Download Reflections on the use of the concept of plasticity in neurobiology. Translation and adaptation by Bruno Will, John Dalrymple-Alford, Mathieu Wolff and Jean-Christophe Cassel from J. Paillard, J Psychol 1976; 1:33-47.
Will, B. E., Dalrymple-Alford, J. C., Wolff, M., Cassel, J. (2008). Reflections on the use of the concept of plasticity in neurobiology. Translation and adaptation by Bruno Will, John Dalrymple-Alford, Mathieu Wolff and Jean-Christophe Cassel from J. Paillard, J Psychol 1976; 1:33-47. Behavioural Brain Research, 192, 6-10. 10.1016/j.bbr.2007.11.008
Download The concept of brain plasticity-Paillard's systemic analysis and emphasis on structure and function (followed by the translation of a seminal paper by Paillard on plasticity).
Will, B., Dalrymple-Alford, J., Wolff, M., Cassel, J. (2008). The concept of brain plasticity-Paillard's systemic analysis and emphasis on structure and function (followed by the translation of a seminal paper by Paillard on plasticity). Behavioural Brain Research, 192(1), 2-7. 10.1016/j.bbr.2007.11.008
Download Anterior but not intralaminar thalamic nuclei support allocentric spatial memory.
Wolff, M., Gibb, S., Cassel, J., Dalrymple-Alford, J. (2008). Anterior but not intralaminar thalamic nuclei support allocentric spatial memory. Neurobiology Learning and Memory, 90(1), 71-80. 10.1016/j.nlm.2008.01.007
Download The extended hippocampal-diencephalic memory system: enriched housing promotes recovery of the flexible use of spatial representations after anterior thalamic lesions.
Wolff, M., Loukavenko, E. A., Will, B. E., Dalrymple-Alford, J.C. (2008). The extended hippocampal-diencephalic memory system: enriched housing promotes recovery of the flexible use of spatial representations after anterior thalamic lesions. Hippocampus, 18, 996-1007. 10.1002/hipo.20457
Download Don't look now or look away: Two sources of saccadic disinhibition in Parkinson's disease?
van Stockum, S., MacAskill, M., Anderson, T., Dalrymple-Alford, J. (2008). Don't look now or look away: Two sources of saccadic disinhibition in Parkinson's disease? Neuropsychologia, 46(13), 3108-3115. 10.1016/j.neuropsychologia.2008.07.002

2007

Heitger, M. H., Jones, R. D., Dalrymple-Alford, J. C., Frampton, C. M., Ardagh, M. W., Anderson, T.J. (2007). Dichotomy between symptom status and quality of life during the first year after mild head injury - intellectual ability influences the perception of recovery. Journal of Rehabilitation Medicine, 39(8), 612 - 621.
Download Mild head injury - a close relationship between motor function at one week post-injury and overall recovery at three and six months.
Heitger, M. H., Jones, R. D., Dalrymple-Alford, J. C., Frampton, C. M., Ardagh, M. W., Anderson, T.J. (2007). Mild head injury - a close relationship between motor function at one week post-injury and overall recovery at three and six months. Journal of the Neurological Sciences, 253, 34-47. 10.1016/j.jns.2006.11.007
Download Sensory-motor and cognitive tests predict driving ability of persons with brain disorders.
Innes, C., Jones, R., Dalrymple-Alford, J., Hayes, S., Hollobon, S., Severinsen, J., Smith, G., Nicholls, A., Anderson, T. (2007). Sensory-motor and cognitive tests predict driving ability of persons with brain disorders. Journal of the Neurological Sciences, 260(1-2), 188-98. 10.1016/j.jns.2007.04.052
Download Towards therapy to relieve memory impairment after anterior thalamic lesions: improved spatial working memory after immediate and delayed postoperative enrichment.
Loukavenko, E. A., Ottley, M. C., Moran, J. P., Wolff, M. , Dalrymple-Alford, J.C. (2007). Towards therapy to relieve memory impairment after anterior thalamic lesions: improved spatial working memory after immediate and delayed postoperative enrichment. European Journal of Neuroscience, 26(11), 3267-3276. 10.1111/j.1460-9568.2007.05879.x

2006

Download Odour-place paired-associate learning and limbic thalamus: Comparison of anterior, lateral and medial thalamic lesions.
Gibb, S. J., Wolff, M. , Dalrymple-Alford, J.C. (2006). Odour-place paired-associate learning and limbic thalamus: Comparison of anterior, lateral and medial thalamic lesions. Behavioral Brain Research, 172(1), 155-168. 10.1016/j.bbr.2006.05.017
Download Motor deficits and recovery during the first year following mild closed head injury.
Heitger, M., Jones, R., Dalrymple-Alford, J. C., Frampton, C. M., Ardagh, M. W. , Anderson, T. (2006). Motor deficits and recovery during the first year following mild closed head injury. Brain Injury, 20, 807-824. 10.1080/02699050600676354
Download Dissociation of egocentric and allocentric spatial processing in medial thalamus.
Mitchell, A. , Dalrymple-Alford, J. (2006). Dissociation of egocentric and allocentric spatial processing in medial thalamus. Learning & Memory, 13, 388-396. 10.1101/lm.122206
Download Lateral and anterior thalamic lesions impair independent memory systems.
Mitchell, A. S. , Dalrymple-Alford, J.C. (2006). Lateral and anterior thalamic lesions impair independent memory systems. Learning and Memory, 13(3), 388-396. 10.1101/lm.122206
Download Beyond spatial memory: the anterior thalamus and memory for the temporal order of a sequence of odor cues.
Wolff, M., Gibb, S. J. , Dalrymple-Alford, J.C. (2006). Beyond spatial memory: the anterior thalamus and memory for the temporal order of a sequence of odor cues. Journal of Neuroscience, 26(11), 2907-2913. 10.1523/JNEUROSCI.5481-05.2006

2005

Download Dissociable memory effects after medial thalamus lesions in the rat.
Mitchell, A. S. , Dalrymple-Alford, J.C. (2005). Dissociable memory effects after medial thalamus lesions in the rat. European Journal of Neuroscience, 22, 973-985. 10.1111/j.1460-9568.2005.04199.x

2004

Download A new rat model of the human serial reaction time task: contrasting effects of caudate and hippocampal lesions.
Christie, M. A. , Dalrymple-Alford, J.C. (2004). A new rat model of the human serial reaction time task: contrasting effects of caudate and hippocampal lesions. Journal of Neuroscience, 24, 1034-1039. 10.1523/JNEUROSCI.3340-03.2004
Download Eye movement and visuomotor arm movement deficits following mild closed head injury.
Heitger, M., Anderson, T., Jones, R., Dalrymple-Alford, J., Frampton, C. , Ardagh, M. (2004). Eye movement and visuomotor arm movement deficits following mild closed head injury. Brain, 127, 575-590. 10.1093/brain/awh066

2003

Download The effects of alcohol on driving-related sensorimotor performance across four times of day.
Dalrymple-Alford, J. C., Kerr, P. A., Jones, R. D. (2003). The effects of alcohol on driving-related sensorimotor performance across four times of day. Journal of Studies on Alcohol, 64, 93-97. 10.15288/jsa.2003.64.93

Abstracts and Short papers

2022

Download TV‐L1 Ordinal Logistic Regression Reveals New Morphometric Patterns Related to Parkinsonian Symptom Severity: An ENIGMA‐PD study.
Zhao, Y., van Heese, E., Laansma, M. A., Al‐Bachari, S., Anderson, T., Assogna, F., ..., Dalrymple-Alford, J., ..., Melzer, T., ..., Pitcher, T., ..., Gutman, B. A. (2022). TV‐L1 Ordinal Logistic Regression Reveals New Morphometric Patterns Related to Parkinsonian Symptom Severity: An ENIGMA‐PD study. Alzheimer's & Dementia, 18, e067037. 10.1002/alz.067037

2020

Download Neuropsychiatric symptoms are associated with dementia in Parkinson’s disease but not predictive of it.
Horne, K.-L., MacAskill, M. R., Myall, D., Livingston, L., Grenfell, S., Pascoe, M. J., Young, B., Shoorangiz, R., Melzer, T. R., Pitcher, T. L., Anderson, T. J., Dalrymple-Alford, J. C. (2020). Neuropsychiatric symptoms are associated with dementia in Parkinson’s disease but not predictive of it. MedRxiv, 2020, 09, 01, 20186312. https://doi.org/10.1101/2020.09.01.20186312

2019

Download Sensorimotor integration assessment by the Symbol-Digit modalities test in patients with Parkinson’s disease.
Alamri Y., Pascoe M. J., MacAskill M. R., Anderson T. J., Dalrymple-Alford J. C. (2019). Sensorimotor integration assessment by the Symbol-Digit modalities test in patients with Parkinson’s disease. Neurosciences 24, 143. 10.17712/nsj.2019.2.20190002

2018

Dalrymple-Alford, J. C., Perry, B. A. L. (2018). Lesions of the mammillothalamic tract and anterior thalamic nuclei: Response to Vann and Nelson (2018). Hippocampus, 28, 694-697. 10.1002/hipo.22963 
Horne, K. L., Myall, D. J., MacAskill, M. R., Anderson, T. J., Dalrymple-Alford, J. C.  (2018). Response to “Parkinson's disease mild cognitive impairment classifications and neurobehavioral symptoms” [letter]. International Psychogeriatrics. 10.1017/S1041610218000091

2016

Horne, K, Myall, DJ, Livingston, L, Grenfell, SF, Melzer, TR, Pitcher, TL, MacAskill, MR, Anderson, TJ, Dalrymple-Alford, JC (2016). Risk of dementia in Parkinson’s disease: Towards optimal short cognitive testing.  Proceedings of the 34th International Winter Conference on Brain Research, 1.
Melzer, TR, Keenan, RJ, Myall, DJ, Kaur, G, Livingston, L, Horne, K, Marsh, S, MacAskill, MR, Dalrymple-Alford, JC, Anderson, TJ (2016). Amyloid imaging and cognition in Parkinson’s disease: Interim report.  Proceedings of the 34th International Winter Conference on Brain Research, 3.
Myall, DJ, Pitcher, TL, MacAskill, MR, Pearson, JF, Lacey, C, Dalrymple-Alford, J C, Anderson, T J (2016). Epidemiology of Parkinson’s in New Zealand: Sex, age, and future burden.  Proceedings of the 34th International Winter Conference on Brain Research,  34, 10, 4.
Pitcher, TL, Myall, DJ, MacAskill, MR, Pearson, JF, Lacey, C, Dalrymple-Alford, J C, Anderson, T J (2016). Ethnic and regional differences in Parkinson’s disease in New Zealand.  Proceedings of the 34th International Winter Conference on Brain Research, 5.

2015

Almuqbel, M, Melzer, TR, Myall, DJ, MacAskill, MR, Livingston, L, Pitcher, TL, Dalrymple-Alford, JC, Anderson, TJ (2015). Longitudinal magnetic resonance spectroscopy in Parkinson’s disease. Proceedings of the 21st Annual Meeting of the Organization for Human Brain Mapping.
Melzer, TR, Myall, DJ, MacAskill, MR, Livingston, L, Pitcher, TL, Watts, R, Keenan, RJ, Dalrymple-Alford, JC, Anderson, TJ (2015). White matter lesions contribute to future dementia in Parkinson’s disease. Proceedings of the 21st Annual Meeting of the Organization for Human Brain Mapping.

2014

Almuqbel, M., Melzer, T., Myall, D., MacAskill, M., Livingston, L., Wood, K., Pitcher, T., Dalrymple-Alford, J. , Anderson, T. (2014). Cognitive status in Parkinsons disease characterised by magnetic resonance spectroscopy.  Proceedings of the International Australasian Winter Conference on Brain Research (AWCBR), Queenstown, New Zealand,  32, 34.
Melzer, T., Myall, D., Livingston L., , Wood, K., Pitcher, T., Keenan, R., MacAskill, M., Dalrymple-Alford, J. , Anderson, T. (2014). White matter lesions - a factor in developing dementia in patients with Parkinsons disease.  Proceedings of the International Australasian Winter Conference on Brain Research (AWCBR), Queenstown, New Zealand, 32, Abstract 3.5.
Myall, D., Wood, K., Livingston, L., Pitcher, T., Melzer, T., MacAskill, M., Anderson, T. , Dalrymple-Alford, J. (2014). Individualised medicine: Predicting dementia in Parkinsons disease.  Proceedings of the International Australasian Winter Conference on Brain Research (AWCBR), Queenstown, New Zealand,  32, Abstract 8.1.
Wood, K., Myall, D., Livingston, L., Melzer, T., Pitcher, T., MacAskill, M., Anderson, T. , Dalrymple-Alford, J. (2014). Comparing mild cognitive impairment criteria in Parkinsons disease: influence on dementia onset.  Proceedings of the International Australasian Winter Conference on Brain Research (AWCBR), Queenstown, New Zealand, 32, Abstract 6.4.

2013

Alamri, Y., MacAskill, M., Myall, D., Dalrymple-Alford, J., & Anderson, T. (2013). Animal-naming in Parkinson's disease (Abstract). 2013 Neuroscience Meeting Planner San Diago, CA: Society for, 431, Program No.10/N5..
Dalrymple-Alford, J. C., Livingston, L., Melzer, T. R., Wood, K., Goh, T. J., Pitcher, T. L., Graham, C. F., Keenan, R. J., MacAskill, M. R. , Anderson, T.J. (2013). Current perspectives on Parkinsons disease: Cognition to the fore.  Proceedings of the 31st Australasian Winter Conference on Brain Research 2013, Queenstown,  Volume 31, Abstract 29.
Dalrymple-Alford, J., McCurrie, C., Anderson, T., Watts, R., MacAskill, M., Pitcher, T., Livingston, L., Keenan, R. , Melzer, T. (2013). Domain specific cognitive dysfunction in Parkinson’s Disease and associated pattern of grey matter atrophy.  Proceedings of the Movement Disorders Society 17th International Congress - Sydney, Abstract 572..
Debernard, L., Alla, S., Melzer, T., Van Stockum, S., Graham, C., Dalrymple-Alford, J., Miller, DH, Mason, D (2013). Cortical perfusion is associated with cognitive function in relapsing remitting multiple sclerosis patients (Abstract).  Multiple Sclerosis,  19(S11), 171. 10.1177/1352458513502429
Grenfell, S., Melzer, T. R., Young, B., Wang, A, Livingston, L., Keenan, R. J., MacAskill, M. R., Anderson, T. J. , Dalrymple-Alford, J.C. (2013). Reduced default mode network connectivity and autobiographical memory in mild cognitive impairment.  Proceedings of the 31st Australasian Winter Conference on Brain Research 2013, Queenstown, Volume 31, Abstract 27.
MacAskill, M., Alamri, Y., Myall, D., Dalrymple-Alford, J., Anderson, T. (2013). Tea with milk and sugar: gaze and action coordination in a real-world task in Parkinsons disease (Abstract). Proceedings of the 17th European Conference on Eye Movement Research, Lund, Journal of Eye Movement Research, 6(3), 512.
Melzer, T. R., Watts, R., MacAskill, M., Pitcher, T., Livingston, L., Keenan, R., Dalrymple-Alford, J. , Anderson, T. (2013). Serial DTI and cognitive decline in Parkinsons disease. Proceedings of the Movement Disorders Society 17th International Congress, Sydney,  Movement Disorders, 28 Supplement 1, 555.
Toh, E., MacAskill, M., Dalrymple-Alford, J., Myall, D., MacLeod, S., Livingston, L. , Anderson, T. (2013). Proceedings of the Movement Disorders Society 17th International Congress, Sydney,  Movement Disorders, 28 Supplement 1, Abstract 758.
Toh, E., MacAskill, M., Dalrymple-Alford, J., Myall, D., MacLeod, S., Livingston, L. , Anderson, T. (2013). Progression in cognitive function of Huntington patients relative to controls: a 12 months study. Proceedings of the Movement Disorders Society 17th International Congress, Sydney, Movement Disorders, 28 Supplement 1, Abstract 760 .
Wood, K., Livingston, L., Melzer, T. R., Pitcher, T. L., MacAskill, M. R., Anderson, T. J. , Dalrymple-Alford, J.C. (2013). Criteria for Parkinson’s disease with mild cognitive impairment associated with increased progression to dementia.  Proceedings of the 31st Australasian Winter Conference on Brain Research 2013, Queenstown,  Volume 31, 58.

2012

Toh, E., MacAskill, M., Dalrymple-Alford, J., Myall, D., Livingston, L., MacLeod, A. , Anderson, T. (2012). Impairment of implicit prediction in rhythmic saccadic movement in symptomatic huntington patients (Abstract). Journal of Neurology, Neurosurgery, and Psychiatry, 83:Suppl 1, A34. 10.1136/jnnp-2012-303524.104
Toh, E., MacAskill, M., Dalrymple-Alford, J., Myall, D., Livingston, L., Ross, J., Anderson, T. (2012). The effectiveness of cognitive and reflexive saccade measures in discriminating Huntingtons disease from healthy controls (Abstract).  European Journal of Neurology, 19 Suppl 1, Poster 1661. 10.1111/j.1468-1331.2012.03888.x